2-pyridine | 215582-96-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 2-pyridine
• 英文别名: 2,2′-(pyridin-2-ylmethylazanediyl) diethanethiol；N,N-bis(mercaptoethyl)(aminomethyl)-2-pyridine；2-(bis(2-mercaptoethyl)aminomethyl)pyridine；2,2'-(pyridin-2-ylmethylazanediyl)diethanethiol；2,2'-(pyridin-2-ylmethylazanedyl)diethanethiol；2-[Pyridin-2-ylmethyl(2-sulfanylethyl)amino]ethanethiol
• CAS: 215582-96-0
• 化学式: C₁₀H₁₆N₂S₂
• 分子量: 228.382
• InChiKey: UCUAOOAPWVJZKR-UHFFFAOYSA-N

物化性质

• 沸点：
  328.4±37.0 °C(Predicted)
• 密度：
  1.139±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.3
• 重原子数：
  14
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  18.1
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  2-pyridine 在 盐酸 、 caesium carbonate 作用下， 以 甲醇 、 水 、 N,N-二甲基甲酰胺 为溶剂， 生成 4-(pyridin-2-ylmethyl)-1,7-dithia-4,10-diazacyclododecane
  参考文献：
  名称：

  Two Hg(II) complexes with a capped trigonal prismatic geometry derived from multidentate macrocyclic ligands containing N and S donors, with coordinated anions

  摘要：

  Two Hg(II) complexes [HgL'(ClO(4))(2)] (1) and [HgL(ClO(4))]ClO(4) (2) derived from the macrocyclic ligands, 4-(pyridin-2-ylmethyl)-1,7-dithia-4,10-diazacyclododecane (L') and 7-(pyridin-2-ylmethyl)-1,4,10-trithia- 7,13-diazacyclopentadecane (L), have been crystallographically characterised. Ligand L and its Hg(II) complex were isolated unexpectedly, and a possible formation pathway of the ligand is proposed. By including weakly bound O atoms from the perchlorate ions, the Hg atoms in both complexes are seven-coordinate and possess capped trigonal prismatic geometries. These uncommon structures for Hg(II) complexes were achieved mainly by the relatively large size of the metal ion and the steric effect from the macrocycles. In both complexes, strong hydrogen bonding between the amine hydrogen atom and a perchlorate ion was observed. For complex 1, the interaction is N(3)-H(15)center dot center dot center dot O(8) at 2.08(12)angstrom where O(8) is of the same anion as one of the coordinated O atoms; in complex 2, a similar hydrogen bond, N(7)-H(7)center dot center dot center dot O(32), with a distance of 2.25(12)angstrom, is formed to the coordinated anion, but the second anion remains discrete. (C) 2010 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.ica.2010.03.066
• 作为产物：
  描述：

  环硫乙烷 、 2-氨甲基吡啶 以 甲苯 为溶剂， 反应 40.0h， 以90%的产率得到2-pyridine
  参考文献：
  名称：

  The iron centre of the cluster-free hydrogenase (Hmd): low-spin Fe(ii) or low-spin Fe(0)?

  摘要：

  红外数据表明，具有两个顺式CO的单铁复合物，以及该酶和模型复合物的莫斯鲍尔数据，支持氢化酶Hmd的无簇铁中心是低自旋Fe(II)的说法。

  DOI：

  10.1039/b805262j

文献信息

• Synthesis of metal-free and zinc phthalocyanines containing 2-pyridyl-methyl pendant arm linked with <font>NS</font>₄-donor macrocyclic moiety and their selectivity towards <font>Cu</font>(<font>II</font>) cations
  作者：Nilgün Kabay、Ümmühan Ocak、Serhat Gün、Yaşar Gök

  DOI：10.1142/s1088424613500600

  日期：2013.6

  New phthalonitrile (L1), metal-free phthalocyanine (H₂Pc) and zinc-phthalocyanine (ZnPc) substituted in peripheral positions with 2-pyridyl methyl pendant arm linked mixed donor macrocyclic ligands have been prepared in a multi-step reaction sequence. The novel compounds were characterized by a combination of elemental anlaysis, ¹ H NMR, ¹³ C NMR, IR, UV-vis and MS spectral data. The influence of metal cations such as Cd ²⁺, Zn ²⁺, Hg ²⁺, Al ³⁺, Fe ³⁺ and Cu ²⁺ on the spectroscopic properties of dinitrile compound L1 and free phthalocyanine H₂Pc was investigated by means of absorption spectrophotometry. Spectrophotometric titrations were carried out with these ligands for Cu ²⁺ ion. The complex composition of Cu - L1 was found 1:1 by means of spectrophotometric titration data. The spectrophotometric method showed good sensitivity for Cu ²⁺ with linear range of 2.6 × 10^-6 to 1.3 × 10^-4 M with dinitrile compound.

  通过多步反应序列制备了外围位置被 2-吡啶基甲基垂臂连接的混合供体大环配体取代的新型酞腈（L1）、无金属酞菁（H2Pc）和锌酞菁（ZnPc）。这些新型化合物的特征通过元素分析、1 H NMR、13 C NMR、IR、UV-vis 和 MS 光谱数据进行了综合分析。通过吸收分光光度法研究了 Cd 2+、Zn 2+、Hg 2+、Al 3+、Fe 3+ 和 Cu 2+ 等金属阳离子对二腈化合物 L1 和游离酞菁 H2Pc 光谱特性的影响。用这些配体对 Cu 2+ 离子进行了分光光度滴定。通过分光滴定数据发现，Cu - L1 的复合物成分为 1:1。分光光度法对 Cu 2+ 具有良好的灵敏度，与二腈化合物的线性范围为 2.6 × 10-6 至 1.3 × 10-4 M。
• Synthesis, structures, electrochemistry and properties of dioxo-molybdenum(VI) and -tungsten(VI) complexes with novel asymmetric N2OS, and partially symmetric N2S2, NOS2 N-capped tripodal ligands
  作者：Yee-Lok Wong、Andrew R. Cowley、Jonathan R. Dilworth

  DOI：10.1016/j.ica.2004.07.008

  日期：2004.12

  A new class of asymmetric N -capped (dianionic/trianionic) tripodal proligands [H x (L n )] ( x = 2, n = 1–6; x = 3, n = 7, 8) which possess pendant arms with N 2 OS, N 2 S 2 or NOS 2 donor groups and with different chelate ring sizes 5,5,5} or 5,6,5} has been prepared. Treatment of these ligands with [WO 2 Cl 2 (dme)] (dme = 1,2-dimethoxyethane) in the presence of base (triethylamine or KOH) leads

  新型的不对称N封端（双阴离子/三向离子）三脚架配体[H x（L n）]（x = 2，n = 1-6； x = 3，n = 7，8），其侧臂带有N已经制备了2个OS，N 2 S 2或NOS 2供体基团，并且具有不同的螯合环尺寸5,5,5}或5,6,5}。在碱（三乙胺或KOH）存在下，用[WO 2 Cl 2（dme）]（dme = 1,2-二甲氧基乙烷）处理这些配体会导致形成[WO]型顺式-二氧杂钨（VI）复合物。 2（L n）]（n = 1-6）和K [WO 2（L n）]（n = 7，8）。这些四齿配体与[MoO 2（acac）2]（acac =乙酰丙酮酸）反应，得到相应的Mo（VI）类似物[MoO 2（L n）]（n = 1-6）和K [MoO 2（L n ）]（n = 7、8）。而且，使用相似的方法合成了具有NS 2三齿配体[MoO 2（L 9）]的新的五坐标二氧钼（VI）配合物。
• Synthesis and characterization of complexes of the {ReO}3+ core with SNS and S donor ligands
  作者：Frank J Femia、Xiaoyuan Chen、Kevin P Maresca、Timothy M Shoup、John W Babich、Jon Zubieta

  DOI：10.1016/s0020-1693(00)00144-4

  日期：2000.8

  [ReOeta(3)-(SCH(2)CH(2))(2)N(CH(2)C(5)H(4)N)}(eta(1)-C(6)H(4)OCH(3)-4-CH(2)S)] (6). Likewise, under similar reaction conditions, the use of the related tridentate ligand, [(HSCH(2)CH(2))(2)N(CH(2)CH(2)C(5)H(4)N)], has led to the isolation of a series of rhenium complexes of the type [ReOeta(3)-(SCH(2)CH(2))(2)N(CH(2)CH(2)C(5)H(4)N)}(eta(1)-C(6)H(4)X-4-S)] (X=Br (7), Cl (8), OCH(3) (9)), as well as [ReOe

  [ReOCl(3)(PPh(3))(2)] 与 N,N-双(2-巯基乙基)苄胺和 4-溴苯硫醇的反应允许分离 [ReOeta(3)-(SCH( 2)CH(2))(2)N(CH(2)C(6)H(5))}-(eta(1)-C(6)H(4)Br-4-S)] (1 ）。[ReOCl(3)(PPh(3))(2)] 与 [(HSCH(2)CH(2))(2)N(CH(2)C(5)H(4)N)] 的反应用三乙胺处理的氯仿中适当的硫醇导致了一系列 [ReOeta(3)-(SCH(2)CH(2))(2)N(CH(2) )C(5)H(4)N)}(eta(1)-C(6)H(4)X-4-S)] (X = Br (2), Cl (3), F (4) , 和 OCH(3) (5)) 和 [ReOeta(3)-(SCH(2)CH(2))(2)N(CH(2)C(5)H(4)N)}( eta(1)-C(6)H(4)OCH(3)-4-CH(2)S)]
• Novel Thiolato-Bridged Tetranuclear Manganese(II) and Iron(II) Complexes with Adamantane-like Cores
  作者：Masahiro Mikuriya、Takanori Kotera

  DOI：10.1246/cl.1998.971

  日期：1998.10

  Thiolato-bridged tetranuclear manganese(II) and iron(II) complexes, [M4Lb3Cl]Cl (M = Mn and Fe; H2Lb = 2-[bis(2-mercaptoethyl)aminomethyl]pyridine), have been isolated and characterized by X-ray crystallography, which reveals an adamantane-like M4S6 core. Magnetic susceptibility data show an overall antiferromagnetic interaction.

  硫醇桥联四核锰（II）和铁（II）复合物[M4Lb3Cl]Cl（M = Mn和Fe；H2Lb = 2-[双（2-巯基乙基）氨基甲基]吡啶）已经分离并通过X射线晶体学进行了表征，该表征揭示了金刚烷状M4S6核心。磁化率数据表明存在整体反铁磁相互作用。
• A novel hexadentate ligand and its complexes with divalent metal ions (Zinc, Copper, and Cobalt): Synthesis, characterization, and electrochemical investigation
  作者：Zhenhong Wei、Xiang Xie、Jia Zhao、Lingman Huang、Xiaoming Liu

  DOI：10.1016/j.ica.2012.01.032

  日期：2012.5

  A novel hexadentate ligand, N-(pyridin-2-ylmethyl)-N,N'-(bis-(2-(pyridin-2-ylmethylthio))ethyethanamine) (L), containing "N4S2" donor-set was synthesized. Its reaction with one equivalent of divalent metal perchlorate salts, M(ClO4)(2)center dot 6H(2)O (M = Zn, Cu, and Co), in methanol yielded three mononuclear complexes [ML](ClO4)(2) (M = Zn, 1; Cu, 2; Co, 3) in octahedral geometry. The complexes were fully characterized and their structures were determined using X-ray single crystal diffraction analysis. UV-Vis spectra of the complexes revealed that metal-to-ligand charge transfer (MLCT) transition bands showed readily red-shift in the trend of Zn(II), Co(II), and Cu(II) complexes. Upon the divalent metal binding, the ligand-based reduction process shifted positively which, otherwise, is not observable in the electrochemical window. (C) 2012 Elsevier B.V. All rights reserved.