2-(2-(3-cyano-5-fluorophenyl)-4-((4-fluoro-N-(2-hydroxyethyl)phenylsulfonamido)methyl)phenoxy)acetic acid | 1260097-34-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-(2-(3-cyano-5-fluorophenyl)-4-((4-fluoro-N-(2-hydroxyethyl)phenylsulfonamido)methyl)phenoxy)acetic acid
• 英文别名: 2-[2-(3-Cyano-5-fluorophenyl)-4-[[(4-fluorophenyl)sulfonyl-(2-hydroxyethyl)amino]methyl]phenoxy]acetic acid
• CAS: 1260097-34-4
• 化学式: C₂₄H₂₀F₂N₂O₆S
• 分子量: 502.495
• InChiKey: FOYUQNDBRUMRPL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  35
• 可旋转键数：
  10
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  136
• 氢给体数：
  2
• 氢受体数：
  10

文献信息

• [EN] BIARYL OXYACETIC ACID COMPOUNDS<br/>[FR] COMPOSÉS D'ACIDE BIARYL OXYACÉTIQUE
  申请人：LIGAND PHARM INC

  公开号：WO2011002814A2

  公开（公告）日：2011-01-06

  Some embodiments of the present invention include novel phenoxyacetic acids useful for the prevention and treatment of inflammatory disorders, including those affecting the respiratory system and skin. Some compounds provided include those of the general formula (I), and compounds of general formula (Ia).