2-Cyclopentyl-2-methylpropanal | 1499937-34-6

• 分子结构分类: 有机化合物 - 有机氧化合物 - 有机氧化物
• 英文名称: 2-Cyclopentyl-2-methylpropanal
• CAS: 1499937-34-6
• 化学式: C₉H₁₆O
• 分子量: 140.22
• InChiKey: GAEDQTPUGBNHBU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  10
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.89
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

文献信息

• [EN] DIAMINO ALCOHOLS AND THEIR USE AS RENIN INHIBITORS<br/>[FR] DIAMINOALCOOLS ET UTILISATION DE CEUX-CI EN TANT QU'INHIBITEURS DE LA RENINE
  申请人：SPEEDEL EXPERIMENTA AG

  公开号：WO2005070877A1

  公开（公告）日：2005-08-04

  The application relates to novel amino alcohols of the general formula (I) where R, R1, R2, R3, R4, R5 and R6 each have the definitions illustrated in detail in the description, to a process for their preparation, and to the use of these compounds as medicines, in particular as renin inhibitors.

  该申请涉及一类新颖的氨基酸醇，其通用公式为(I)，其中R、R1、R2、R3、R4、R5和R6的定义在描述中详细说明，还涉及这些化合物的制备方法，以及将这些化合物用作药物，特别是作为肾素抑制剂的使用。
• Amido-aminoalcohols as therapeutic compounds
  申请人：Speedel Experimenta AG

  公开号：EP1745777A1

  公开（公告）日：2007-01-24

  Use of compounds of the general formula (I) in which R, R1, R2, R3, R4, R5, X1 and X2 have the definitions illustrated in detail in the description, as beta-secretase, cathepsin D, plasmepsin II and/or HIV protease inhibitors.

  使用一般式(I)中R、R1、R2、R3、R4、R5、X1和X2的化合物作为β-秘鲁酶、蛋白酶D、质膜素II和/或HIV蛋白酶抑制剂。这些定义在详细说明中。
• Amino alcohol derivatives and their activity as renin inhibitors
  申请人：Herold Peter

  公开号：US20070155743A1

  公开（公告）日：2007-07-05

  The application relates to novel amino alcohols of general formula (I) where R, R 1 , R 2 , R 3 , R 4 , R 5 ,X 1 and X 2 each have the definitions illustrated in detail in the description, to a process for their preparation and to the use of these compounds as medicines, in particular as renin inhibitors.

  本申请涉及一种新型氨基醇，其一般式为（I），其中R、R1、R2、R3、R4、R5、X1和X2分别具有详细描述中所示的定义，以及它们的制备方法和这些化合物作为药物的用途，特别是作为肾素抑制剂。
• Amido-amino alcohols as therapeutic compounds
  申请人：Herold Peter

  公开号：US20070021399A1

  公开（公告）日：2007-01-25

  Use of compounds of the general formula (I) in which R, R 1 , R 2 , R 3 , R 4 , R 5 , X 1 and X 2 have the definitions illustrated in detail in the description, as beta-secretase, cathepsin D, plasmepsin II and/or HIV protease inhibitors.

  使用一般式(I)中的化合物，其中R、R1、R2、R3、R4、R5、X1和X2的定义在描述中详细说明，作为β-秘密酶、猫hepsin D、plasmepsin II和/或HIV蛋白酶抑制剂。
• Diamino alcohols as therapeutic compounds
  申请人：Herold Peter

  公开号：US20070021413A1

  公开（公告）日：2007-01-25

  Use of compounds of the general formula (I) in which R, R 1 , R 2 , R 3 , R 4 , R 5 , and R 6 have the definitions illustrated in detail in the description, as beta-secretase, cathepsin D, plasmepsin II and/or HIV protease inhibitors.

  使用通式(I)中的化合物，其中R，R1，R2，R3，R4，R5和R6的定义在描述中详细说明，作为β-秘鲁蛋白酶，猫hepsin D，血浆酶II和/或HIV蛋白酶抑制剂。