4-dimethylamino-N,N,N'-tris(trimethylsilyl)benzamidine | 117357-80-9

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 4-dimethylamino-N,N,N'-tris(trimethylsilyl)benzamidine
• 英文别名: 4-(dimethylamino)-N,N,N'-tris(trimethylsilyl)benzenecarboximidamide
• CAS: 117357-80-9
• 化学式: C₁₈H₃₇N₃Si₃
• 分子量: 379.768
• InChiKey: XJDOOCDJPGSIOK-UHFFFAOYSA-N

物化性质

• 沸点：
  393.3±44.0 °C(Predicted)
• 密度：
  0.88±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  5.31
• 重原子数：
  24.0
• 可旋转键数：
  5.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.61
• 拓扑面积：
  18.84
• 氢给体数：
  0.0
• 氢受体数：
  2.0

反应信息

• 作为反应物：
  描述：

  3-p-methoxyphenyl-1,1,5,5-tetramethyl-1H-1,5-diazapentadienium perchlorate 、 4-dimethylamino-N,N,N'-tris(trimethylsilyl)benzamidine 在 吡啶 、 potassium fluoride 作用下， 以84%的产率得到2-(4-dimethylaminophenyl)-5-(4-methoxyphenyl)-pyrimidine
  参考文献：
  名称：

  An Efficient New Pyrimidine Synthesis - a pathway to octupoles

  摘要：

  The condensation of N,N,N'-tris(trimethylsilyl)amidines (6, 11, 22) with vinamidinium salts (1, 7) in the presence of potassium fluoride is the method of choice for the synthesis of pyrimidines (8, 12, 20, 23). Octupoles comprising 1,3,5-benzene (8) and triphenylamine (12, 20) derivatives can be prepared in high yields.

  DOI：

  10.1002/prac.19963380187
• 作为产物：
  描述：

  三甲基氯硅烷 、 lithium hexamethyldisilazane 、 4-(二甲胺基)苄腈 生成 4-dimethylamino-N,N,N'-tris(trimethylsilyl)benzamidine
  参考文献：
  名称：

  An Efficient New Pyrimidine Synthesis - a pathway to octupoles

  摘要：

  The condensation of N,N,N'-tris(trimethylsilyl)amidines (6, 11, 22) with vinamidinium salts (1, 7) in the presence of potassium fluoride is the method of choice for the synthesis of pyrimidines (8, 12, 20, 23). Octupoles comprising 1,3,5-benzene (8) and triphenylamine (12, 20) derivatives can be prepared in high yields.

  DOI：

  10.1002/prac.19963380187

文献信息

• Synthesis of Oligo(diazaphenyls). Tailor-Made Fluorescent Heteroaromatics and Pathways to Nanostructures
  作者：Rudolf Gompper、Hans-Jürgen Mair、Kurt Polborn

  DOI：10.1055/s-1997-1405

  日期：1997.6

  Oligoaza derivatives of biphenyl, terphenyl, quaterphenyl, quinquephenyl, sexiphenyl, septiphenyl, octiphenyl, noviphenyl, deciphenyl and dodeciphenyl and poly(pyrimidinylenephenylene) can be synthesized from readily accessible vinamidinium salts and amidines or N,N,N'-tris(trimethylsilyl)amidines. The fluorescence of these systems can be tuned over a wide spectral range by varying number and positions of N atoms. Oligo(diazaphenyls) are thermally and photochemically stable, are easier to reduce than oligophenyls, can be dissolved at any rate in strong acids and show strong blue fluorescence in solution as well as in the solid state.

  苯并、联苯、四苯、五苯、六苯、七苯、八苯、九苯、十苯和十二苯的寡氮杂衍生物以及聚(嘧啶亚苯基亚苯)可以从易得的乙烯胺盐和胺或N,N,N'-三(三甲基硅基)胺合成。通过改变N原子的数量和位置，这些体系的荧光可以在广泛的光谱范围内调节。寡(二氮苯)在热和光化学上是稳定的，比寡苯更容易还原，在强酸中可以以任意速率溶解，并且在溶液中以及固态中显示强烈的蓝色荧光。