2-mesityl-6-(2-methoxyphenyl)-4-phenylphosphinine | 883448-64-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-mesityl-6-(2-methoxyphenyl)-4-phenylphosphinine
• 英文别名: 2-(2-methoxyphenyl)-4-phenyl-6-(2,4,6-trimethylphenyl)phosphinine
• CAS: 883448-64-4
• 化学式: C₂₇H₂₅OP
• 分子量: 396.469
• InChiKey: OUEGZMCIDAFUNM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.2
• 重原子数：
  29.0
• 可旋转键数：
  4.0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.15
• 拓扑面积：
  9.23
• 氢给体数：
  0.0
• 氢受体数：
  1.0

反应信息

• 作为反应物：
  描述：

  2-mesityl-6-(2-methoxyphenyl)-4-phenylphosphinine 在 三溴化硼 作用下， 以 二氯甲烷 为溶剂， 以35.4%的产率得到2-mesityl-6-(2-hydroxyphenyl)-4-phenylphosphinine
  参考文献：
  名称：

  Chiral bidentate phosphabenzene-based ligands: synthesis, coordination chemistry, and application in Rh-catalyzed asymmetric hydrogenations

  摘要：

  Novel hydroxy-functionalized phosphabenzenes were synthesized, which provide the possibility to prepare chiral phosphabenzene-phosphites. These systems act as bidentate ligands toward rhodium centers and the corresponding metal complexes were applied in the rhodium-catalyzed asymmetric hydrogenation of prochiral substrates. (c) 2006 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2006.01.049
• 作为产物：
  描述：

  3-phenyl-1-(2,4,6-trimethylphenyl)-2-propen-1-one 在 tetrafluoroboric acid 、 氘代3-氨基-5-吗啉-4-甲基-恶唑-2-啉酮 作用下， 以 乙醚 、 1,2-二氯乙烷 、 乙腈 为溶剂， 反应 9.0h， 生成 2-mesityl-6-(2-methoxyphenyl)-4-phenylphosphinine
  参考文献：
  名称：

  Chiral bidentate phosphabenzene-based ligands: synthesis, coordination chemistry, and application in Rh-catalyzed asymmetric hydrogenations

  摘要：

  Novel hydroxy-functionalized phosphabenzenes were synthesized, which provide the possibility to prepare chiral phosphabenzene-phosphites. These systems act as bidentate ligands toward rhodium centers and the corresponding metal complexes were applied in the rhodium-catalyzed asymmetric hydrogenation of prochiral substrates. (c) 2006 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2006.01.049