(S)-3-(2-ethyl-4-{5-[5-ethyl-6-(isopropyl-methyl-amino)-pyridin-3-yl]-[1,2,4]oxadiazol-3-yl}-6-methyl-phenoxy)-propane-1,2-diol | 1186617-98-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: (S)-3-(2-ethyl-4-{5-[5-ethyl-6-(isopropyl-methyl-amino)-pyridin-3-yl]-[1,2,4]oxadiazol-3-yl}-6-methyl-phenoxy)-propane-1,2-diol
• 英文别名: (S)-3-(2-Ethyl-4-{5-[5-ethyl-6-(isopropyl-methyl-amino)-pyridin-3-yl]-[1,2,4]oxadiazol-3-yl}-6-methyl-phenoxy)-propan-1,2-diol；(2S)-3-[2-ethyl-4-[5-[5-ethyl-6-[methyl(propan-2-yl)amino]pyridin-3-yl]-1,2,4-oxadiazol-3-yl]-6-methylphenoxy]propane-1,2-diol
• CAS: 1186617-98-0
• 化学式: C₂₅H₃₄N₄O₄
• 分子量: 454.569
• InChiKey: SWTCVBCKPCCVPL-NRFANRHFSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.3
• 重原子数：
  33
• 可旋转键数：
  10
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.48
• 拓扑面积：
  105
• 氢给体数：
  2
• 氢受体数：
  8

文献信息

• [EN] PYRIDINE COMPOUNDS<br/>[FR] COMPOSÉS DE PYRIDINE
  申请人：ACTELION PHARMACEUTICALS LTD

  公开号：WO2009109906A1

  公开（公告）日：2009-09-11

  The invention relates to pyridine compounds, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunomodulating agents.

  这项发明涉及吡啶化合物，它们的制备以及它们作为药用活性化合物的用途。这些化合物特别作为免疫调节剂。
• PYRIDINE COMPOUNDS
  申请人：Bolli Martin

  公开号：US20110028448A1

  公开（公告）日：2011-02-03

  The invention relates to pyridine compounds, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunomodulating agents.

  该发明涉及吡啶化合物，其制备和用作药物活性化合物。这些化合物特别作为免疫调节剂。