3-[Acryloyl-(3-dimethylamino-propyl)-amino]-propionic acid tert-butyl ester | 879573-42-9

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 3-[Acryloyl-(3-dimethylamino-propyl)-amino]-propionic acid tert-butyl ester
• CAS: 879573-42-9
• 化学式: C₁₅H₂₈N₂O₃
• 分子量: 284.399
• InChiKey: QEWZRXSQUNMQPG-UHFFFAOYSA-N

反应信息

• 作为反应物：
  描述：

  3-[Acryloyl-(3-dimethylamino-propyl)-amino]-propionic acid tert-butyl ester 在 N,N-二异丙基乙胺 作用下， 以 甲醇 、 二氯甲烷 为溶剂， 反应 51.0h， 生成 3-[[3-(Acryloyl-isobutyl-amino)-propionyl]-(3-dimethylamino-propyl)-amino]-propionic acid tert-butyl ester
  参考文献：
  名称：

  Antimicrobial β-peptoids by a block synthesis approach

  摘要：

  Antimicrobial peptides and their mimetics offer a potential new disinfective tool. beta-Peptoids (oligo-N-substituted beta-alanines) were synthesized and investigated for antimicrobial activity. A block approach whereby di- and tri-beta-peptoids were first prepared and then ligated via amide bond formation to synthesize larger beta-peptoids was developed. The beta-peptoids were found to possess moderate activity in an Escheridchia coli assay. (C) 2005 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmcl.2005.11.075
• 作为产物：
  描述：

  丙烯酸叔丁酯 、 alkaline earth salt of/the/ methylsulfuric acid 在 N,N-二异丙基乙胺 作用下， 以 甲醇 、 二氯甲烷 为溶剂， 反应 50.0h， 生成 3-[Acryloyl-(3-dimethylamino-propyl)-amino]-propionic acid tert-butyl ester
  参考文献：
  名称：

  Antimicrobial β-peptoids by a block synthesis approach

  摘要：

  Antimicrobial peptides and their mimetics offer a potential new disinfective tool. beta-Peptoids (oligo-N-substituted beta-alanines) were synthesized and investigated for antimicrobial activity. A block approach whereby di- and tri-beta-peptoids were first prepared and then ligated via amide bond formation to synthesize larger beta-peptoids was developed. The beta-peptoids were found to possess moderate activity in an Escheridchia coli assay. (C) 2005 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmcl.2005.11.075