2-(N-Pyrryl)-propionamid | 89943-16-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯
• 英文名称: 2-(N-Pyrryl)-propionamid
• 英文别名: 2-pyrrol-1-yl-propionic acid amide；2-Pyrrol-1-yl-propionsaeure-amid；I+/--Methyl-1H-pyrrole-1-acetamide；2-pyrrol-1-ylpropanamide
• CAS: 89943-16-8
• 化学式: C₇H₁₀N₂O
• 分子量: 138.169
• InChiKey: UJUQWXOUSFCLPL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.1
• 重原子数：
  10
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  48
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 在 ammonium hydroxide 作用下， 生成 2-(N-Pyrryl)-propionamid
  参考文献：
  名称：

  The Synthesis of 1- and 2-Pyrrolealkylamines

  摘要：

  DOI：

  10.1021/jo01114a020

文献信息

• N-Alkanoylaminomethyl and N-Aroylaminomethyl pyrrole insecticidal and acaricidal agents
  申请人：AMERICAN CYANAMID COMPANY

  公开号：EP0530515A1

  公开（公告）日：1993-03-10

  This invention relates to N-alkanoylaminomethyl and N-aroylaminomethyl pyrrole compounds of formula I It also relates to the use of said compounds as insecticidal and acaricidal agents and to a method of protecting plants from attack by insects and acarina by application of an N-alkanoylaminomethyl or N-aroylaminomethyl pyrrole to said plants or to the locus in which they are growing.

  本发明涉及式 I 的 N-烷酰氨基甲基和 N-芳酰氨基甲基吡咯化合物 本发明还涉及上述化合物作为杀虫和杀螨剂的用途，以及通过对上述植物或植物生长的地点施用 N-烷酰氨基甲基或 N-芳酰基氨基甲基吡咯来保护植物免受昆虫和螨虫侵袭的方法。
• Process for the preparation of N-halomethylpyrrole and intermediates
  申请人：BASF AKTIENGESELLSCHAFT

  公开号：EP0530515B1

  公开（公告）日：2002-11-06
• THIENOPYRROLE DERIVATIVES FOR USE IN TARGETING PROTEINS, COMPOSITIONS, METHODS, AND USES THEREOF
  申请人：Biotheryx, Inc.

  公开号：EP3559005A1

  公开（公告）日：2019-10-30
• US5130328A
  申请人：——

  公开号：US5130328A

  公开（公告）日：1992-07-14
• [EN] THIENOPYRROLE DERIVATIVES FOR USE IN TARGETING PROTEINS, COMPOSITIONS, METHODS, AND USES THEREOF<br/>[FR] DÉRIVÉS DE THIÉNOPYRROLE DESTINÉS À ÊTRE UTILISÉS DANS LE CIBLAGE DE PROTÉINES, COMPOSITIONS, PROCÉDÉS ET UTILISATIONS ASSOCIÉS
  申请人：BIOTHERYX INC

  公开号：WO2018118947A1

  公开（公告）日：2018-06-28

  The present invention provides compounds that modulate protein function, to restore protein homeostasis, including cytokine, CKla, GSPTl, aiolos, and/or ikaros activity, and cell-cell adhesion. The invention provides methods of modulating protein-mediated diseases, such as cytokine-mediated diseases, disorders, conditions, or responses. Compositions, including in combination with other cytokine and inflammatory mediators, are provided. Methods of treatment, amelioration, or prevention of diseases, disorders, or conditions associated with a protein, such as diseases, disorders, and conditions associated with cytokines, including inflammation, fibromyalgia, rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, psoriasis, psoriatic arthritis, inflammatory bowel diseases, Crohn's disease, ulcerative colitis, uveitis, inflammatory lung diseases, chronic obstructive pulmonary disease, Alzheimer's disease, and cancer, are provided.