1-methanesulfonyloxy-non-4-yne | 68275-04-7

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机磺酸及其衍生物
• 英文名称: 1-methanesulfonyloxy-non-4-yne
• 英文别名: Non-4-ynyl methanesulfonate
• CAS: 68275-04-7
• 化学式: C₁₀H₁₈O₃S
• 分子量: 218.317
• InChiKey: FOXVIRHTPFXWLL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  14
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  51.8
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  1-methanesulfonyloxy-non-4-yne 在 lithium bromide 作用下， 以 丙酮 为溶剂， 生成 1-bromo-non-4-yne
  参考文献：
  名称：

  Preparation of halo enol phostones by reaction of acetylenic phosphonate monoesters with (bis-collidine)halo hexafluorophosphate

  摘要：

  Reaction of non-conjugated acetylenic phosphonate monoesters with (bis-collidine) bromo and iodo hexafluorophosphates was found to lead to the formation of halo enol phostones. Depending on the size of the heterocyclic compounds formed (6-8-membered compounds), endo or a mixture of endo and exo cyclization products were obtained. (c) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2008.06.037
• 作为产物：
  描述：

  壬-4-炔-1-醇 、 甲基磺酰氯 在 三乙胺 作用下， 以 乙醚 为溶剂， 生成 1-methanesulfonyloxy-non-4-yne
  参考文献：
  名称：

  Preparation of halo enol phostones by reaction of acetylenic phosphonate monoesters with (bis-collidine)halo hexafluorophosphate

  摘要：

  Reaction of non-conjugated acetylenic phosphonate monoesters with (bis-collidine) bromo and iodo hexafluorophosphates was found to lead to the formation of halo enol phostones. Depending on the size of the heterocyclic compounds formed (6-8-membered compounds), endo or a mixture of endo and exo cyclization products were obtained. (c) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2008.06.037

文献信息

• Synth�se d'alcools ac�tyl�niques par alkylation d'hydroxy-?-alkynes-1
  作者：Jacques Flahaut、Philippe Miginiac

  DOI：10.1002/hlca.19780610635

  日期：1978.9.20

  Synthesis of acetylenic alcohols by alkylation of ω‐hydroxy‐1‐alkynesIn liquid ammonia and with lithium amide, the alkylation of an ω‐hydroxyl‐alkyne proceeds with good yield with primary or secondary alcohols and with fair yield with tertiary alcohols. It is a very convenient way to prepare many substituted acetylenic alcohols.
• FLAHAUT J.; MIGINIAC P., HELV. CHIM. ACTA, 1978, 61, NO 6, 2275-2285
  作者：FLAHAUT J.、 MIGINIAC P.

  DOI：——

  日期：——