4-Chlor-2-(1-cyan-1-methylethylamino)-6-isopropylamino-5-pyrimidin-carbonitril | 66308-94-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪类
• 英文名称: 4-Chlor-2-(1-cyan-1-methylethylamino)-6-isopropylamino-5-pyrimidin-carbonitril
• 英文别名: 4-chloro-2-(1-cyano-1-methyl-ethylamino)-6-isopropylamino-pyrimidine-5-carbonitrile；4-chloro-2-(1-cyano-1-methylethylamino)-6-isopropylamino-5-pyrimidinecarbonitrile；4-chloro-2-(2-cyanopropan-2-ylamino)-6-(propan-2-ylamino)pyrimidine-5-carbonitrile
• CAS: 66308-94-9
• 化学式: C₁₂H₁₅ClN₆
• 分子量: 278.744
• InChiKey: XCSCQXMNCVOTCG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  19
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  97.4
• 氢给体数：
  2
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  4-Chlor-2-(1-cyan-1-methylethylamino)-6-isopropylamino-5-pyrimidin-carbonitril 在 sodium 作用下， 以 甲醇 、 乙醚 、 水 为溶剂， 生成 2-(1-cyano-1-methyl-ethylamino)-4-isopropylamino-6-methoxy-pyrimidine-5-carbonitrile
  参考文献：
  名称：

  Herbicidal 5-pyrimidinecarbonitriles

  摘要：

  在2和6位置具有氨基取代基，4位置具有烷氧基取代基的5-嘧啶腈类化合物具有除草活性。描述了在这一类中制备新型活性化合物和中间体；阐明了含有活性化合物的除草组合物；并揭示了利用这些除草组合物控制植物生长的方法。

  公开号：

  US04092150A1
• 作为产物：
  描述：

  异丙胺 、 4,6-Dichlor-2-(1-Cyan-1-methylethylamino)-5-pyrimidin-carbonitril 在 丙酮 、 乙醚 、 水 、 magnesium sulfate 、 甲基环己烷 作用下， 以 丙酮 为溶剂， 反应 16.0h， 以to give 2.7 grams of 4-chloro-2-(1-cyano-1-methylethylamino)-6-isopropylamino-5-pyrimidinecarbonitrile的产率得到4-Chlor-2-(1-cyan-1-methylethylamino)-6-isopropylamino-5-pyrimidin-carbonitril
  参考文献：
  名称：

  Herbicidal 5-pyrimidinecarbonitriles

  摘要：

  2和6位有氨基取代基，4位有烷氧基取代基的5-嘧啶羧腈具有除草活性。本文描述了这一类新型活性化合物和中间体的制备方法，阐述了含有活性化合物的除草剂组合物，并揭示了利用除草剂组合物控制植物生长的方法。

  公开号：

  US04092150A1

文献信息

• Mononuclear iron complex and organic synthesis reaction using same
  申请人：KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION

  公开号：US10363551B2

  公开（公告）日：2019-07-30

  A mononuclear iron bivalent complex having iron-silicon bonds, which is represented by formula (1), can exhibit an excellent catalytic activity in at least one reaction selected from three reactions, i.e., a hydrosilylation reaction, a hydrogenation reaction and a reaction for reducing a carbonyl compound. (In the formula, R1 to R6 independently represent a hydrogen atom, an alkyl group which may be substituted by X, or the like; X represents a halogen atom, or the like; L1 represents at least one two-electron ligand selected from an isonitrile ligand, an amine ligand, an imine ligand, a nitrogenated heterocyclic ring, a phosphine ligand, a phosphite ligand and a sulfide ligand, wherein, when multiple L1's are present, two L1's may be bonded to each other; L2 represents a two-electron ligand that is different from a CO ligand or the above-mentioned L1, wherein, when multiple L2's are present, two L2's may be bonded to each other; and m1 represents an integer of 1 to 4 and m2 represents an integer of 0 to 3, wherein the sum total of m1 and m2 (i.e., m1+m2) satisfies 3 or 4.)

  具有铁-硅键的单核二价铁络合物，其由公式（1）表示，可以在三个反应中选择至少一个反应表现出优异的催化活性，即硅氢化反应、氢化反应和还原羰基化合物的反应。 （在公式中，R1至R6独立代表氢原子、可能被X取代的烷基团等；X代表卤素原子等；L1代表至少一种从异腈配体、胺配体、亚胺配体、氮杂环、膦配体、亚磷酸盐配体和硫化物配体中选择的两电子配体，其中，当存在多个L1时，两个L1可以相互连接；L2代表与CO配体或上述L1不同的两电子配体，其中，当存在多个L2时，两个L2可以相互连接；m1代表1至4的整数，m2代表0至3的整数，其中m1和m2的总和（即m1+m2）满足3或4。）
• MONONUCLEAR IRON COMPLEX AND ORGANIC SYNTHESIS REACTION USING SAME
  申请人：KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION

  公开号：US20160023196A1

  公开（公告）日：2016-01-28

  Provided is a mononuclear iron complex that comprises an iron-silicon bond that is represented by formula (1) and that exhibits excellent catalyst activity in each of a hydrosilylation reaction, a hydrogenation reaction, and reduction of a carbonyl compound. In formula (1), R 1 -R 6 either independently represent an alkyl group, an aryl group, an aralkyl group or the like that may be substituted with a hydrogen atom or X, or represent a crosslinking substituent in which at least one pair comprising one of R 1 -R 3 and one of R 4 -R 6 is combined. X represents a halogen atom, an organoxy group, or the like. L represents a two-electron ligand other than CO. When a plurality of L are present, the plurality of L may be the same as or different from each other. When two L are present, the two L may be bonded to each other. n and m independently represent an integer of 1 to 3 with the stipulation that n+m equals 3 or 4.

  提供的是一种含有铁硅键的单核铁配合物，其由式（1）表示，并且在氢硅烷基化反应、加氢反应和醛类化合物还原反应中表现出优异的催化活性。 在式（1）中，R1-R6分别独立表示可以用氢原子或X取代的烷基、芳基、芳基烷基等，或表示至少包括一个由R1-R3和一个由R4-R6组成的一对的交联取代基。X表示卤素原子、有机氧基等。L表示除CO之外的双电子配体。当存在多个L时，这些L可以相同也可以不同。当存在两个L时，这两个L可以与彼此相连。n和m分别表示1到3的整数，且n+m等于3或4。
• MONONUCLEAR RUTHENIUM COMPLEX AND ORGANIC SYNTHESIS REACTION USING SAME
  申请人：KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION

  公开号：US20160023197A1

  公开（公告）日：2016-01-28

  Provided is a mononuclear ruthenium complex that comprises a ruthenium-silicon bond that is represented by formula (1) and that exhibits excellent catalyst activity in each of a hydrosilylation reaction, a hydrogenation reaction, and reduction of a carbonyl compound. In formula (1), R 1 -R 6 either independently represent an alkyl group, an aryl group, an aralkyl group or the like that may be substituted with a hydrogen atom or X, or represent a crosslinking substituent in which at least one pair comprising one of R 1 -R 3 and one of R 4 -R 6 is combined. X represents a halogen atom, an organoxy group, or the like. L represents a two-electron ligand other than CO and phosphine. When a plurality of L are present, the plurality of L may be the same as or different from each other. When two L are present, the two L may be bonded to each other. n and m independently represent an integer of 1 to 3 with the stipulation that n+m equals 3 or 4.

  提供的是一种单核钌配合物，其中包含一个由公式（1）表示的钌-硅键，该键在氢硅化反应、氢化反应和羰基化合物还原反应中表现出优异的催化活性。 在公式（1）中，R1-R6分别独立地表示可以用氢原子或X取代的烷基、芳基、芳基烷基或类似物，或表示至少有一对由R1-R3和R4-R6中的一个组成的交联取代基。X表示卤素原子、有机氧基或类似物。L表示除CO和膦以外的双电子配体。当存在多个L时，多个L可以相同或不同。当存在两个L时，两个L可以与彼此键合。n和m分别表示1至3的整数，且n+m等于3或4。
• x Mangave plant named ‘Navajo Princess’
  申请人：Hansen Hans A

  公开号：USPP031136P2

  公开（公告）日：2019-11-26

  A new and unique x Mangave plant named ‘Navajo Princess’ characterized by a medium mound of broad, semi-fleshy, longitudinally folded, stiff and upright to outright foliage. The variegated foliage has greyed-green centers with creamy white margins and a frosty green zone between, and with greyed-purple spots toward base that intensify with strong ultraviolet light. Leaves have small, flexible marginal teeth. The new plant is suitable for the garden or as a potted plant in the garden or home.

  一种名为“纳瓦霍公主”的新型独特的xMangave植物，其特点是中等大小的圆锥形、宽阔的、半肉质的、纵向折叠的、坚挺而直立的叶子。有斑驳的叶子，中心为灰绿色，边缘为乳白色，中间有一片霜绿色区域，基部有灰紫色斑点，在强紫外线下颜色更加强烈。叶子有小而柔软的边缘齿。这种新植物适合种植在花园或作为盆栽植物在家中或花园中使用。
• GRAFT POLYMER, RESIN COLORED MATTER, METHOD FOR PRODUCING SAME, AND RESIN COMPOSITION CONTAINING RESIN COLORED MATTER
  申请人：Wako Pure Chemical Industries, Ltd.

  公开号：EP3165541A1

  公开（公告）日：2017-05-10

  Provided are: a graft polymer and a colored resin that are free from color migration or fading caused by bleed-out after coloring, which is a defect of a dye, without impairing vivid color development and transparency of the dye; a method for producing the same; and a resin composition containing the colored resin. The present invention relates to: (1) a graft polymer that has a polyolefin (A) as the main chain, and a polymer (B) polymerized a dye (b) having a radical reactive functional group, in a side chain; (2) the graft polymer which is characterized in that the dye (b) having the radical reactive functional group is a cationic rhodamine derivative, a cationic triarylmethane-type dye derivative or a cationic cyanine-type dye derivative, having an ethylenically unsaturated group; (3) a colored resin consisting of the graft polymer; as well as (4) a method for producing the colored resin, which is characterized by mixing the polyolefin (A), the dye (b) having the radical reactive functional group, and the radical reaction initiator (C), and subjecting a radical reaction of the mixture; and the like.

  本发明提供了：一种接枝聚合物和有色树脂，它们在不损害染料的鲜艳显色性和透明性的情况下，不会因着色后的渗色（染料的缺陷）而导致颜色迁移或褪色；一种生产方法；以及一种含有该有色树脂的树脂组合物。 本发明涉及(1)一种接枝聚合物，其主链为聚烯烃(A)，侧链为聚合了具有自由基活性官能团的染料(b)的聚合物(B)；(2)该接枝聚合物，其特征在于具有自由基活性官能团的染料(b)是阳离子罗丹明衍生物、阳离子三芳基甲烷型染料衍生物或阳离子氰基型染料衍生物，具有乙烯不饱和基团；(3) 由接枝聚合物组成的有色树脂；以及 (4) 生产有色树脂的方法，其特征在于将聚烯烃 (A)、具有自由基活性官能团的染料 (b) 和自由基反应引发剂 (C) 混合，并使混合物发生自由基反应；等等。