11-mercaptoundecanoyl chloride | 54654-13-6

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 酰卤
• 英文名称: 11-mercaptoundecanoyl chloride
• 英文别名: 11-Sulfanylundecanoyl chloride
• CAS: 54654-13-6
• 化学式: C₁₁H₂₁ClOS
• 分子量: 236.806
• InChiKey: UHSVDEJBTHNBLO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.8
• 重原子数：
  14
• 可旋转键数：
  10
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.91
• 拓扑面积：
  18.1
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  11-mercaptoundecanoyl chloride 、 6-[(Tridecylamino)methyl]pyrimidine-2,4(1H,3H)-dione 在 吡啶 作用下， 以 氯仿 为溶剂， 生成 11-Mercapto-undecanoic acid butyl-(2,6-dioxo-1,2,3,6-tetrahydro-pyrimidin-4-ylmethyl)-amide
  参考文献：
  名称：

  异超分子化学：纳米晶体和分子共价和非共价组装和组织的合成策略

  摘要：

  描述了纳米晶体的制备和可以在溶液中共价或非共价组装的分子的合成，以产生具有明确定义的杂超分子功能的杂超分子。还描述了制备和合成方法，其产生具有可寻址的异超分子功能的杂化超分子的有组织的组装。最后，概述了这些合成策略的发展，以允许共价和非共价组装和组织多种缩合相和分子组分。

  DOI：

  10.1002/hlca.19980810511
• 作为产物：
  描述：

  11-巯基十一烷酸 在 氯化亚砜 作用下， 以 gaseous matrix 为溶剂， 反应 0.17h， 生成 11-mercaptoundecanoyl chloride
  参考文献：
  名称：

  Amide and ester surface attachment reactions for alkanethiol monolayers at gold surfaces as studied by polarization modulation Fourier transform infrared spectroscopy

  摘要：

  The modification of alkanethiol monolayers via amide and ester formation reactions is demonstrated as a methodology for attaching monolayer and submonolayer coverages of specific chemical species onto metal electrodes. A monolayer of 11-mercaptoundecanoic acid (HSC10H20COOH) is used as a surface bifunctional linking agent on polycrystalline gold surfaces. The reaction of these adsorbed molecules with gaseous thionyl chloride converts the carboxylic acid group to an acid chloride which can then be reacted further with an amine or alcohol to form an amide or ester linkage. The attachment of alkyl, aromatic, and electrochemically active species to the surface is reported to demonstrate the versatility of this surface derivatization chemistry. Polarization modulation Fourier transform infrared (PM-FTIR) spectroscopy is employed as the primary method for monitoring the chemical structure of the adsorbed monolayers, and additional X-ray photoelectron spectroscopy (XPS) and electrochemical measurements are used to verify the elemental composition, oxidation state, and surface coverage of the adsorbed molecules.

  DOI：

  10.1021/ac00028a003

文献信息

• System and method for Raman spectroscopy assay using paramagnetic particles
  申请人：Carron T. Keith

  公开号：US20060240572A1

  公开（公告）日：2006-10-26

  A Raman spectroscopy technique allows an analyte, a paramagnetic particle, and a spectral enhancement particle to combine in solution and for the combination product to be localized by a magnetic field for analysis. The spectral enhancement particle may be comprised of an active SERS metal particle with or without a material coating. The spectral enhancement particle may function as a reporter for the presence of the analyte or merely increase the magnitude of the Raman spectrum of the analyte. The technique is applicable to both immunoassays and chemical assays. Multiple spectral enhancement particle reporters may be measured in a single assay that can detect multiple analytes using the SERS effect.

  拉曼光谱技术允许分析物、顺磁性粒子和光谱增强粒子在溶液中结合，并通过磁场对结合产物进行定位分析。光谱增强粒子可由带或不带材料涂层的活性 SERS 金属粒子组成。光谱增强粒子可以作为分析物存在的报告器，也可以仅仅增加分析物拉曼光谱的幅度。该技术适用于免疫测定和化学分析。利用 SERS 效果检测多种分析物的单一检测方法可以测量多个光谱增强粒子报告器。
• US9494581B2
  申请人：——

  公开号：US9494581B2

  公开（公告）日：2016-11-15