(R)-N-Allyl-2,3-dihydro-1H-inden-1-amine oxalate | 1166392-43-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 茚满类
• 英文名称: (R)-N-Allyl-2,3-dihydro-1H-inden-1-amine oxalate
• 英文别名: oxalic acid;(1R)-N-prop-2-enyl-2,3-dihydro-1H-inden-1-amine
• CAS: 1166392-43-3
• 化学式: C14H17NO4
• 分子量: 263.29
• InChiKey: KGFWCWSROCOLAN-UTONKHPSSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.61
• 重原子数：
  19
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  86.6
• 氢给体数：
  3
• 氢受体数：
  5

文献信息

• PROCESS FOR THE SYNTHESIS OF PROPARGYLATED AMINOINDAN DERIVATIVES
  申请人：Cipla Limited

  公开号：EP2231582B1

  公开（公告）日：2011-06-22
• Process for the Synthesis of Propargylated Aminoindan Derivatives
  申请人：Phull Manjinder Singh

  公开号：US20110054218A1

  公开（公告）日：2011-03-03

  A process for preparing a compound of formula (V) or its enantiomer, which comprises: (a) reacting racemic aminoindan of formula (II) or its enantiomer with allylhalide in presence of a base and an organic solvent at a temperature ranging from 25 C to the reflux temperature of the solvent to give compound of formula (III); Where R is H or (b) reacting the compound (III) with halogenating agent in a suitable organic solvent to give a dihalo compound of formula (IV). (c) treating the dihalo compound (IV) with a suitable base to give compound (V).
• US8461388B2
  申请人：——

  公开号：US8461388B2

  公开（公告）日：2013-06-11