N-acetylglycyl-Nε,Nε-di-[2-(α-D-mannopyranosyloxy)ethyl]-L-lysyl-L-alanine | 1171113-25-9

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: N-acetylglycyl-Nε,Nε-di-[2-(α-D-mannopyranosyloxy)ethyl]-L-lysyl-L-alanine
• CAS: 1171113-25-9
• 化学式: C₂₉H₅₂N₄O₁₇
• 分子量: 728.748
• InChiKey: ILRGCXCQOXIMRD-MXYXXRDYSA-N

反应信息

• 作为产物：
  描述：

  (2S)-2-[[(2S)-2-[(2-acetamidoacetyl)amino]-6-[bis[2-[(2S,3S,4S,5R,6R)-3,4,5-triacetyloxy-6-(acetyloxymethyl)oxan-2-yl]oxyethyl]amino]hexanoyl]amino]propanoic acid 在 甲醇 、 sodium methylate 、 Amberlite IR₁₂₀ 作用下， 以 甲醇 为溶剂， 以21 mg的产率得到N-acetylglycyl-Nε,Nε-di-[2-(α-D-mannopyranosyloxy)ethyl]-L-lysyl-L-alanine
  参考文献：
  名称：

  Reductive Amination of the Lysine N ^ε-Amino Group Leads to a Bivalent Glyco-Amino Acid Building Block Suited for SPPS

  摘要：

  Aiming at the synthesis of structurally altered glycopeptides to probe multivalency effects in carbohydrate recognition, a glyco-amino acid building block was prepared, carrying a bivalent carbohydrate branching unit. This new mannosylated lysine derivative was shown to be fully suitable for solid-phase peptide synthesis.

  DOI：

  10.1080/07328300902874795