1-Aryl-5-alkyl pyrazole derivative compounds, processes of making and methods of using thereof
申请人：Lee Ik Hyoung
公开号：US20080031902A1
公开（公告）日：2008-02-07
Provided are 1-aryl-5-alkyl pyrazole compounds, of formula (I):
wherein: R
1
is hydrogen, cyano, halogen, R
8
, formyl, —C(O)R
8
, —C(O)OR
8
, —C(O)NR
9
R
10
, or —C(S)NH
2
; R
2
is R
2
or —S(O)
m
R
11
; R
3
is methyl, ethyl or C
1
-C
4
haloalkyl; R
4
, R
5
and R
7
are independently hydrogen, halogen, alkyl, haloalkyl, cyano or nitro; R
6
is halogen, alkyl, haloalkyl, alkoxy, haloalkyloxy, cyano, nitro, —C(O)R
12
, —S(O)
n
R
12
or SF
5
; Z is a nitrogen atom or C—R
13
; R
8
is alkyl, haloalkyl, cycloalkyl or halocycloalkyl; R
9
is hydrogen, alkyl, haloalkyl or alkoxy; R
10
is hydrogen, alkyl, haloalkyl or alkoxy; R
11
is alkyl, haloalkyl, alkenyl, haloalkenyl, alkynyl, haloalkynyl or cycloalkyl; R
12
is alkyl or haloalkyl; R
13
is hydrogen, halogen, cyano, nitro, alkyl, haloalkyl, alkoxy or haloalkoxy; m is 0, 1 or 2; and n is 0, 1 or 2; or a salt thereof, the method of making compounds of formula (I) and the use of these compounds against ectoparasites, endoparasites and pests.
提供了1-芳基-5-烷基吡唑化合物，化学式为(I)：其中：R1为氢、氰基、卤素、R8、甲酰基、—C(O)R8、—C(O)OR8、—C(O)NR9R10或—C(S)NH2；R2为R2或—S(O)mR11；R3为甲基、乙基或C1-C4卤代烷基；R4、R5和R7独立地为氢、卤素、烷基、卤代烷基、氰基或硝基；R6为卤素、烷基、卤代烷基、烷氧基、卤代烷氧基、氰基、硝基、—C(O)R12、—S(O)nR12或SF5；Z为氮原子或C—R13；R8为烷基、卤代烷基、环烷基或卤代环烷基；R9为氢、烷基、卤代烷基或烷氧基；R10为氢、烷基、卤代烷基或烷氧基；R11为烷基、卤代烷基、烯基、卤代烯基、炔基、卤代炔基或环烷基；R12为烷基或卤代烷基；R13为氢、卤素、氰基、硝基、烷基、卤代烷基、烷氧基或卤代烷氧基；m为0、1或2；n为0、1或2；或其盐，制备化合物(I)的方法以及这些化合物对外寄生虫、内寄生虫和害虫的用途。
