10-bromo-7-butyl-2,4-difluoro-7-methyl-7H-benzo[c]fluoren-5-ol | 1311274-82-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 菲及其衍生物
• 英文名称: 10-bromo-7-butyl-2,4-difluoro-7-methyl-7H-benzo[c]fluoren-5-ol
• 英文别名: 10-Bromo-7-butyl-2,4-difluoro-7-methylbenzo[c]fluoren-5-ol
• CAS: 1311274-82-4
• 化学式: C₂₂H₁₉BrF₂O
• 分子量: 417.293
• InChiKey: YKEUCKYUCGZPAY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.8
• 重原子数：
  26
• 可旋转键数：
  3
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.27
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• METHODS OF MAKING FUSED RING COMPOUNDS
  申请人：He Meng

  公开号：US20120157678A1

  公开（公告）日：2012-06-21

  The present invention relates to methods of making fused ring compounds, such as indeno-fused naphthols, and fused ring indenopyran compounds, such as indeno-fused naphthopyrans, that each employ an unsaturated compound represented by the following Formula II. Referring to the unsaturated compound of Formula II: Ring-A can be selected from optionally substituted aryl (e.g., phenyl); m can be, for example, from 0 to 4; R 1 for each m can be selected from optionally substituted hydrocarbyl (e.g., C 1 -C 6 alkyl) optionally interrupted with at least one linking group (e.g., —O—); and R 3 and R 16 can each be independently selected from, for example, hydrogen or optionally substituted hydrocarbyl, such as C 1 -C 8 alkyl. When Ring-A is a phenyl group, the unsaturated compound represented by Formula II can be referred to as an unsaturated indanone acid/ester compound, or an indenone acid/ester compound (depending on whether R 16 is hydrogen, or an optionally substituted hydrocarbyl group).

  本发明涉及制备融合环化合物的方法，例如吲哚并螺酚和融合环吲哚吡喃化合物，例如吲哚并萘吡喃，每种方法都使用以下化合物II表示的不饱和化合物。关于化合物II的不饱和化合物：环-A可以选择从可选取代芳基（例如苯基）中选择；m可以例如从0到4；每个m的R1可以选择从可选取代的碳氢化合物（例如C1-C6烷基），可选地中断至少一个连接基（例如-O-）；R3和R16可以各自独立地选择，例如氢或可选取代的碳氢化合物，例如C1-C8烷基。当环-A是苯基时，由化合物II表示的不饱和化合物可以称为不饱和吲哚酮酸/酯化合物或吲哚酮酸/酯化合物（取决于R16是氢还是可选取代的碳氢基团）。
• Methods of making fused ring compounds
  申请人：Transitions Optical, Inc.

  公开号：US10689317B2

  公开（公告）日：2020-06-23

  The present invention relates to methods of making fused ring compounds, such as indeno-fused naphthols, and fused ring indenopyran compounds, such as indeno-fused naphthopyrans, that each employ an unsaturated compound represented by the following Formula II. Referring to the unsaturated compound of Formula II: Ring-A can be selected from optionally substituted aryl (e.g., phenyl); m can be, for example, from 0 to 4; R1 for each m can be selected from optionally substituted hydrocarbyl (e.g., C1-C6 alkyl) optionally interrupted with at least one linking group (e.g., —O—); and R3 and R16 can each be independently selected from, for example, hydrogen or optionally substituted hydrocarbyl, such as C1-C8 alkyl. When Ring-A is a phenyl group, the unsaturated compound represented by Formula II can be referred to as an unsaturated indanone acid/ester compound, or an indenone acid/ester compound (depending on whether R16 is hydrogen, or an optionally substituted hydrocarbyl group).

  本发明涉及制造熔融环化合物（如茚并熔合萘酚）和熔融环茚并吡喃化合物（如茚并熔合萘并吡喃）的方法，其中每种化合物都采用下式 II 所代表的不饱和化合物。 关于式 II 的不饱和化合物：环-A 可以选自任选取代的芳基（如苯基）；m 可以是例如 0 至 4；每个 m 的 R1 可以选自任选取代的烃基（如 C1-C6 烷基），任选与至少一个连接基团（如 -O-）间断；R3 和 R16 可以各自独立地选自例如氢或任选取代的烃基，如 C1-C8 烷基。当环-A 为苯基时，式 II 所代表的不饱和化合物可称为不饱和茚酮酸/酯化合物或茚酮酸/酯化合物（取决于 R16 是氢还是任选取代的烃基）。
• INDENO- FUSED RING COMPOUNDS HAVING PHOTOCHROMIC PROPERTIES
  申请人：Transitions Optical, Inc.

  公开号：EP2651913A1

  公开（公告）日：2013-10-23
• INDENO-FUSED RING COMPOUNDS HAVING PHOTOCHROMIC PROPERTIES
  申请人：Transitions Optical, Inc.

  公开号：EP2651913B1

  公开（公告）日：2017-04-19
• Indeno-fused ring compounds
  申请人：He Meng

  公开号：US20110140056A1

  公开（公告）日：2011-06-16

  The present invention relates to compounds represented by the following Formulas (I) and (II), Ring-A of Formulas I and II can be, for example, an aryl group, and Q′ and Q′″ can each be independently selected from groups, such as, halogen, —OH, —CN, amine groups, amide groups, carboxylic acid ester groups, carboxylic acid groups, alkenyl groups, alkynyl groups, carbonate groups, sulfide groups, and sulfonic acid ester groups. The present invention also relates to photochromic compositions and photochromic articles that include one or more photochromic compounds, such as represented by Formula II.