(2S)-2-amino-3-phenylpropanoic acid;sulfuric acid | 79679-86-0

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: (2S)-2-amino-3-phenylpropanoic acid;sulfuric acid
• CAS: 79679-86-0
• 化学式: C9H13NO6S
• 分子量: 263.27
• InChiKey: KLRWOUZEYNJFEP-QRPNPIFTSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.01
• 重原子数：
  17
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  146
• 氢给体数：
  4
• 氢受体数：
  7

文献信息

• Process for racemizing an optically active alpha-amino acid or a salt thereof
  申请人：Tanabe Seiyaku Co., Ltd.

  公开号：EP0057092A1

  公开（公告）日：1982-08-04

  A process for producing a DL-a-amino acid or a salt thereof which comprises racemizing an optically active a-amino acid or a salt thereof in the presence of an aliphatic acid and an aldehyde.

  一种生产 DL-a-氨基酸或其盐的工艺，包括在脂肪族酸和醛的存在下，对光学活性 a-氨基酸或其盐进行消旋化。
• Hybrid polypeptides with selectable properties
  申请人：Amylin Pharmaceuticals Inc.

  公开号：EP2330124A2

  公开（公告）日：2011-06-08

  The present invention relates generally to novel, selectable hybrid polypeptides useful as agents for the treatment and prevention of metabolic diseases and disorders which can be alleviated by control plasma glucose levels, insulin levels, and/or insulin secretion, such as diabetes and diabetes-related conditions. Such conditions and disorders include, but are not limited to, hypertension, dyslipidemia, cardiovascular disease, eating disorders, insulin-resistance, obesity, and diabetes mellitus of any kind, including type 1, type 2, and gestational diabetes.

  本发明一般涉及新型可选择杂交多肽，可作为治疗和预防代谢性疾病和紊乱的药物，这些疾病和紊乱可通过控制血浆葡萄糖水平、胰岛素水平和/或胰岛素分泌来缓解，如糖尿病和糖尿病相关疾病。这些疾病包括但不限于高血压、血脂异常、心血管疾病、饮食失调、胰岛素抵抗、肥胖和任何类型的糖尿病，包括 1 型、2 型和妊娠糖尿病。
• Process for the production of fine chemicals
  申请人：BASF Plant Science GmbH

  公开号：EP2434019A1

  公开（公告）日：2012-03-28

  The present invention relates to a process for the production of the fine chemical in a microorgansm, a plant cell, a plant, a plant tissue or in one or more parts thereof. The invention furthermore relates to nucleic acid molecules, polypeptides, nucleic acid constructs, vectors, antisense molecules, antibodies, host cells, plant tissue, propagtion material, harvested material, plants, microorganisms as well as agricultural compositions and to their use.

  本发明涉及在微生物、植物细胞、植物、植物组织或其一个或多个部分中生产精细化学品的工艺。本发明还涉及核酸分子、多肽、核酸构建体、载体、反义分子、抗体、宿主细胞、植物组织、繁殖材料、收获材料、植物、微生物以及农业组合物及其用途。
• Peptide and polypeptide inhibitors of complement C1s
  申请人：——

  公开号：US20020102256A1

  公开（公告）日：2002-08-01

  The complement system plays an important role in providing resistance to infections and in the pathogenesis of tissue injury. Yet an inappropriate activation of complement can result in a variety of disorders. The present invention provides C1s catalytic site-directed moieties, C1s exosite binding moieties, and bivalent polypeptide inhibitors comprising such moieties, which can be used to treat conditions characterized by inappropriate complement activation.

  补体系统在提供抗感染能力和组织损伤的发病机制方面发挥着重要作用。然而，不适当地激活补体可导致各种疾病。本发明提供了 C1s 催化位点定向分子、C1s 外合物结合分子以及包含这些分子的二价多肽抑制剂，可用于治疗以不适当的补体激活为特征的疾病。
• Preparation and use of cyclic and branched peptides and their labelled derivatives as therapeutic agents, cholecystokinin agonists or antagonists, and diagnostic agents to identify and locate tumours
  申请人：——

  公开号：US20040254339A1

  公开（公告）日：2004-12-16

  This patent application describes the preparation of cyclic and branched peptides of general formula (I) and their conjugated derivatives labelled with a paramagnetic or radioactive metal. The compounds of the present invention are used as diagnostic agents to identify and locate primary tumours and their metastases which over-express type A and/or B cholecystokinin receptors, and as therapeutic agents and cholecystokinin agonists or antagonists.

  本专利申请描述了通式（I）的环状和支链肽及其与顺磁性或放射性金属标记的共轭衍生物的制备方法。本发明的化合物可用作诊断药剂，用于识别和定位过度表达 A 型和/或 B 型胆囊收缩素受体的原发性肿瘤及其转移瘤，也可用作治疗药剂和胆囊收缩素激动剂或拮抗剂。