2,3-Dihydro-3-methyl-2-oxo-1H-indole-3-acetic acid | 933684-19-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 英文名称: 2,3-Dihydro-3-methyl-2-oxo-1H-indole-3-acetic acid
• 英文别名: 2-(3-methyl-2-oxo-1H-indol-3-yl)acetic acid
• CAS: 933684-19-6
• 化学式: C₁₁H₁₁NO₃
• 分子量: 205.21
• InChiKey: YCFHIVUNXHLXEN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.7
• 重原子数：
  15
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.27
• 拓扑面积：
  66.4
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• Heteroaryl-substituted 1,3-dihydroindol-2-one derivatives and medicaments containing them
  申请人：Lubisch Wilfried

  公开号：US20070021607A1

  公开（公告）日：2007-01-25

  The present invention relates to novel 1,3-dihydroindol-2-one (oxindole) derivatives of the formula (I) in which A, R 3 , R 4 , R 5 , R 6 and R 7 are defined according to claim 1 , and to medicaments containing them for the treatment of diseases. In particular, the novel oxindole derivaties can be used for the control and/or prophylaxis of various vasopressin-dependent or oxytocin-dependent diseases.

  本发明涉及公式(I)的新型1,3-二氢吲哚-2-酮(氧吲哚)衍生物，其中A、R3、R4、R5、R6和R7根据权利要求1所定义，并且含有这些衍生物的药物可用于治疗疾病。特别是，这些新型氧吲哚衍生物可用于控制和/或预防各种依赖于血管加压素或催产素的疾病。
• Heteroaryl-substituted 1,3-dihydroindol-2-one derivatives and medicaments containing Them
  申请人：Lubisch Wilfried

  公开号：US20070185126A1

  公开（公告）日：2007-08-09

  The present invention relates to novel 1,3-dihydroindol-2-one (oxindole) derivatives of the formula (I) in which A, R 3 , R 4 , R 5 R 6 and R 7 are defined according to claim 1, and to medicaments containing them for the treatment of diseases. In particular, the novel oxindole derivatives can be used for the control and/or prophylaxis of various vasopressin-dependent or oxytocin-dependent diseases.

  本发明涉及式(I)的新型1,3-二氢吲哚-2-酮（氧化吲哚）衍生物，其中A、R3、R4、R5R6和R7如权利要求1所定义，并且包含它们的药物用于治疗疾病。特别地，这些新型氧化吲哚衍生物可用于控制和/或预防各种依赖于加压素或催产素的疾病。
• HETEROARYL-SUBSTITUTED 1,3-DIHYDROINDOL-2-ONE DERIVATIVES AND MEDICAMENTS CONTAINING THEM
  申请人：Abbott GmbH & Co. KG

  公开号：US20140187543A1

  公开（公告）日：2014-07-03

  The present invention relates to novel 1,3-dihydroindol-2-one (oxindole) derivatives of the formula (I) in which A, R 3 , R 4 , R 5 , R 6 and R 7 are defined according to claim 1 , and to medicaments containing them for the treatment of diseases. In particular, the novel oxindole derivaties can be used for the control and/or prophylaxis of various vasopressin-dependent or oxytocin-dependent diseases.

  本发明涉及一种新型的1,3-二氢吲哚-2-酮（氧化吲哚）衍生物，其化学式为（I），其中A、R3、R4、R5、R6和R7根据权利要求1所定义，并且含有它们的药物可用于治疗疾病。特别地，这些新型的氧化吲哚衍生物可用于控制和/或预防各种依赖于加压素或催产素的疾病。
• US7902379B2
  申请人：——

  公开号：US7902379B2

  公开（公告）日：2011-03-08
• US8350055B2
  申请人：——

  公开号：US8350055B2

  公开（公告）日：2013-01-08