(5Z,10Z)-6,10-Dihydroxy-14-methyl-oxacyclotetradeca-5,10-diene-2,4,12-trione | 151510-03-1

• 分子结构分类: 有机化合物 - 有机杂环化合物
• 英文名称: (5Z,10Z)-6,10-Dihydroxy-14-methyl-oxacyclotetradeca-5,10-diene-2,4,12-trione
• CAS: 151510-03-1
• 化学式: C₁₄H₁₈O₆
• 分子量: 282.293
• InChiKey: FIYDWEIYULWHJL-SQXCDDPUSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  20.0
• 可旋转键数：
  0.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  100.9
• 氢给体数：
  2.0
• 氢受体数：
  6.0

反应信息

• 作为反应物：
  描述：

  (5Z,10Z)-6,10-Dihydroxy-14-methyl-oxacyclotetradeca-5,10-diene-2,4,12-trione 在 potassium carbonate 作用下， 以 甲醇 为溶剂， 反应 1.0h， 以3%的产率得到10-Hydroxy-3-methyl-3,4,7,8-tetrahydro-6H-2-oxa-phenanthrene-1,5-dione
  参考文献：
  名称：

  Synthetic studies on naphthopyrans from a polyketide lactone

  摘要：

  Naphthopyrans, one of which is a synthetic precursor of antifungal semivioxanthin, have been synthesized from a 14-membered polyketide lactone by the intramolecular aldolization,

  DOI：

  10.1016/s0040-4039(00)74057-3
• 作为产物：
  描述：

  8-Methyl-1,2,3,4,5,8,9,10-octahydro-7-oxa-cyclohepta[f]inden-6-one 在 二甲基硫 、 臭氧 作用下， 生成 (5Z,10Z)-6,10-Dihydroxy-14-methyl-oxacyclotetradeca-5,10-diene-2,4,12-trione
  参考文献：
  名称：

  Synthesis and characterization of a 14-membered polyketide lactone

  摘要：

  A stable 14-membered polyketide lactone having a C-methyl group at C- 1 3 has been synthesized and elucidated to have the bis-enol structure by X-ray crystallographic analysis, and its hydride reduction to the tetraols has also been described.

  DOI：

  10.1016/s0040-4039(00)74056-1