dodecane-1-sulfonic acid [10-(2-amino-ethyl)-5,11-dioxo-7-(N'-phenyl-hydrazinocarbonyl)-2,3,5,10,11,11a-hexahydro-1H-benzo[e]pyrrolo[1,2-a][1,4]diazepin-2-yl]-amide | 1170684-77-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯二氮卓类
• 英文名称: dodecane-1-sulfonic acid [10-(2-amino-ethyl)-5,11-dioxo-7-(N'-phenyl-hydrazinocarbonyl)-2,3,5,10,11,11a-hexahydro-1H-benzo[e]pyrrolo[1,2-a][1,4]diazepin-2-yl]-amide
• CAS: 1170684-77-1
• 化学式: C₃₃H₄₈N₆O₅S
• 分子量: 640.847
• InChiKey: OPSHROAOIYKPME-FIBWVYCGSA-N

反应信息

• 作为产物：
  描述：

  (6aS,8S)-5-(2-aminoethyl)-N-[3-(dimethylamino)propyl]-8-(dodecylsulfonylamino)-6,11-dioxo-6a,7,8,9-tetrahydropyrrolo[2,1-c][1,4]benzodiazepine-2-carboxamide 在 三氟乙酸 作用下， 以 二氯甲烷 为溶剂， 反应 0.42h， 生成 dodecane-1-sulfonic acid [10-(2-amino-ethyl)-5,11-dioxo-7-(N'-phenyl-hydrazinocarbonyl)-2,3,5,10,11,11a-hexahydro-1H-benzo[e]pyrrolo[1,2-a][1,4]diazepin-2-yl]-amide
  参考文献：
  名称：

  Solid-phase synthesis of benzodiazepinediones mimicking the C-terminus of the H-Ras protein

  摘要：

  A combined solution and solid-phase method for the synthesis of benzodiazelpinediones mimicking the lipid-modified C-terminus of the H-Ras protein was developed. By means of this 14-step sequence, a collection of 42 peptidomimetics was synthesized. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2009.01.016