(5S,12S)-5,12-bis(benzyloxymethyl)-2,4,13,15-tetraoxahexadecan-8-ol | 1066376-24-6

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: (5S,12S)-5,12-bis(benzyloxymethyl)-2,4,13,15-tetraoxahexadecan-8-ol
• CAS: 1066376-24-6
• 化学式: C₂₈H₄₂O₇
• 分子量: 490.637
• InChiKey: JBFVTMBXWLFXRV-UWDVWBIHSA-N

反应信息

• 作为反应物：
  描述：

  (5S,12S)-5,12-bis(benzyloxymethyl)-2,4,13,15-tetraoxahexadecan-8-ol 在 戴斯-马丁氧化剂 作用下， 以 二氯甲烷 为溶剂， 反应 3.0h， 以88%的产率得到(5S,12S)-5,12-bis(benzyloxymethyl)-2,4,13,15-tetraoxahexadecan-8-one
  参考文献：
  名称：

  Stereoselective synthesis of 1,6-dioxaspiro[4.5]decane chiral spiroketal skeleton via C2-symmetric approach using crossmetathesis

  摘要：

  A common asymmetric approach for the synthesis of a 1,6-dioxaspiro[4.5]decane chiral spiroketal system, which is a subunit of various natural products, is described and the key aspects of the synthesis are self-crossmetathesis and exploitation of C-2-symmetric of the metathesis product 5 to obtain the required chiral spiroketal. (C) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetasy.2008.07.010
• 作为产物：
  描述：

  (5S,12S)-5,12-bis(benzyloxymethyl)-2,4,13,15-tetraoxahexadec-8-ene 在 dimethyl sulfide borane 、 sodium hydroxide 、 双氧水 作用下， 以 四氢呋喃 、 水 为溶剂， 以85%的产率得到(5S,12S)-5,12-bis(benzyloxymethyl)-2,4,13,15-tetraoxahexadecan-8-ol
  参考文献：
  名称：

  Stereoselective synthesis of 1,6-dioxaspiro[4.5]decane chiral spiroketal skeleton via C2-symmetric approach using crossmetathesis

  摘要：

  A common asymmetric approach for the synthesis of a 1,6-dioxaspiro[4.5]decane chiral spiroketal system, which is a subunit of various natural products, is described and the key aspects of the synthesis are self-crossmetathesis and exploitation of C-2-symmetric of the metathesis product 5 to obtain the required chiral spiroketal. (C) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetasy.2008.07.010