| 1318934-18-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• CAS: 1318934-18-7
• 化学式: C₁₄H₂₅F₂NNiOP₂
• 分子量: 381.993
• InChiKey: CUUVJIJASAFIKV-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为反应物：
  描述：

  一氧化碳 、 以 四氢呋喃 为溶剂， 生成 dicarbonylbis(trimethylphosphine)nickel(0)
  参考文献：
  名称：

  Carbonylative formation of N-acetyl-2,6-difluorobenzamide through N–H bond activation of 2,6-difluorobenzamide with Ni(II) complex supported with phosphine ligands

  摘要：

  Fluorinated imide, N-acetyl-2,6-difluorobenzamide (C6H3F2-2,6)C(O)NHC(O) Me 2, could be obtained through one-pot reaction of NiMe2(PMe3)(3) with 2,6-difluorobenzamide (C6H3F2-2,6)C(O)NH2 1 in CO atmosphere. A postulated reaction mechanism via N-H bond cleavage and carbonylative reductive elimination on nickel center was partly experimentally confirmed. An important intermediate (C6H3F2-2,6)C(O)HNNiMe(PMe3)(2) 3 was isolated and structurally characterized. (C) 2011 Elsevier B. V. All rights reserved.

  DOI：

  10.1016/j.jorganchem.2011.04.035
• 作为产物：
  描述：

  [bis(methyl)tris(trimethylphosphane)nickel(II)] 、 2,6-二氟苯甲酰胺 以 四氢呋喃 为溶剂， 以66.2%的产率得到
  参考文献：
  名称：

  Carbonylative formation of N-acetyl-2,6-difluorobenzamide through N–H bond activation of 2,6-difluorobenzamide with Ni(II) complex supported with phosphine ligands

  摘要：

  Fluorinated imide, N-acetyl-2,6-difluorobenzamide (C6H3F2-2,6)C(O)NHC(O) Me 2, could be obtained through one-pot reaction of NiMe2(PMe3)(3) with 2,6-difluorobenzamide (C6H3F2-2,6)C(O)NH2 1 in CO atmosphere. A postulated reaction mechanism via N-H bond cleavage and carbonylative reductive elimination on nickel center was partly experimentally confirmed. An important intermediate (C6H3F2-2,6)C(O)HNNiMe(PMe3)(2) 3 was isolated and structurally characterized. (C) 2011 Elsevier B. V. All rights reserved.

  DOI：

  10.1016/j.jorganchem.2011.04.035