| 1193357-23-1

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• CAS: 1193357-23-1
• 化学式: C₁₈H₃₄O₃
• 分子量: 298.466
• InChiKey: DAWKVHLZRWHFGP-QVKBXKRDSA-N

反应信息

• 作为产物：
  描述：

  、 2,2-二甲氧基丙烷 在 对甲苯磺酸 作用下， 以 水 为溶剂， 反应 4.0h， 以5 mg的产率得到
  参考文献：
  名称：

  Cytotoxic eremophilane sesquiterpenoids from the saprobic fungus Berkleasmium nigroapicale BCC 8220

  摘要：

  Berkleasmins A-E, five new eremophilane sesquiterpenoids were isolated from the saprobic fungus Berkleasmium nigroapicale BCC 8220. The structures of the new compounds were elucidated by analyses of NMR spectroscopic and mass spectrometry data in combination with chemical means. Berkleasmins A and C exhibited cytotoxic activity against cancer cell-lines (NCI-H187, MCF-7, and KB) as well as nonmalignant Vero cells with IC(50) values of 1.1-7.5 mu g/mL, and these compounds also showed antimalarial activity with respective IC(50) of 3.1 and 2.8 mu g/mL. (c) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2009.08.077