(2S)-2-amino-4-(1,3-dioxolan-2-yl)butanoic acid | 1590431-70-1

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: (2S)-2-amino-4-(1,3-dioxolan-2-yl)butanoic acid
• CAS: 1590431-70-1
• 化学式: C₇H₁₃NO₄
• 分子量: 175.185
• InChiKey: LNTKVSCXTSGAEH-YFKPBYRVSA-N

物化性质

• 沸点：
  328.2±27.0 °C(Predicted)
• 密度：
  1.250±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -3
• 重原子数：
  12
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  81.8
• 氢给体数：
  2
• 氢受体数：
  5

文献信息

• ALDEHYDE ACETAL BASED PROCESSES FOR THE MANUFACTURE OF MACROCYCLIC DEPSIPEPTIDES AND NEW INTERMEDIATES
  申请人：ACEMOGLU Murat

  公开号：US20140100353A1

  公开（公告）日：2014-04-10

  The invention relates to a method or process for the chemical manufacture of depsipeptides of the formula I employing an aldehyde acetal intermediate, wherein the symbols have the meaning defined in the description, to new intermediates and their manufacture, as well as related invention embodiments.

  该发明涉及一种利用醛缩合物中间体的化学制备depsipeptides的方法或过程，其中符号的含义如描述中所定义，以及新的中间体及其制备方法，以及相关的发明实施形式。
• Novel Aldehyde Acetal Based Processes for the Manufacture of Macrocyclic Depsipeptides and New Intermediates
  申请人：ACEMOGLU Murat

  公开号：US20170022254A1

  公开（公告）日：2017-01-26

  The invention relates to process for the chemical manufacture of depsipeptides of the formula (I) employing an aldehyde acetal intermediate, (Formula I) wherein the symbols have the meaning defined in the description, to new intermediates and their manufacture, as well as related invention embodiments.
• US8987413B2
  申请人：——

  公开号：US8987413B2

  公开（公告）日：2015-03-24
• [EN] ALDEHYDE ACETAL BASED PROCESSES FOR THE MANUFACTURE OF MACROCYCLIC DEPSIPEPTIDES AND NEW INTERMEDIATES<br/>[FR] PROCÉDÉS BASÉS SUR DE L'ACÉTAL D'ALDÉHYDE POUR LA FABRICATION DE DEPSIPEPTIDES MACROCYCLIQUES, ET NOUVEAUX INTERMÉDIAIRES ASSOCIÉS
  申请人：NOVARTIS AG

  公开号：WO2014057419A2

  公开（公告）日：2014-04-17

  The invention relates to a method or process for the chemical manufacture of depsipeptides of the formula I employing an aldehyde acetal intermediate Formula (I), wherein the symbols have the meaning defined in the description, to new intermediates and their manufacture, as well as related invention embodiments.
• [EN] NOVEL ALDEHYDE ACETAL BASED PROCESSES FOR THE MANUFACTURE OF MACROCYCLIC DEPSIPEPTIDES AND NEW INTERMEDIATES<br/>[FR] PROCÉDÉS BASÉS SUR DE L'ACÉTAL D'ALDÉHYDE POUR LA FABRICATION DE DEPSIPEPTIDES MACROCYCLIQUES ET NOUVEAUX INTERMÉDIAIRES ASSOCIÉS
  申请人：NOVARTIS AG

  公开号：WO2015155676A1

  公开（公告）日：2015-10-15

  The invention relates to process for the chemical manufacture of depsipeptides of the formula (I) employing an aldehyde acetal intermediate, (Formula I) wherein the symbols have the meaning defined in the description, to new intermediates and their manufacture, as well as related invention embodiments.