| 175648-39-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• CAS: 175648-39-2
• 化学式: C₁₀H₁₃LiO
• 分子量: 156.154
• InChiKey: UCQIJNORZLIAQI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.66
• 重原子数：
  12.0
• 可旋转键数：
  1.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  9.23
• 氢给体数：
  0.0
• 氢受体数：
  1.0

反应信息

• 作为反应物：
  描述：

  (R)-[6'-(dichlorophosphoryl)-6,2'-dimethoxybiphenyl-2-yl]phosphonic acid dichloride 、 以 四氢呋喃 为溶剂， 反应 0.5h， 生成
  参考文献：
  名称：

  Alkoxy substituted MeO-BIPHEP-type diphosphines ligands for asymmetric hydrogenation of aryl ketones

  摘要：

  In this paper, a series of optically active MeO-BIPHEP-type ligands, (S)-6,6'-dimethoxy-2,2'-bis(di-p-alkoxyphenylphosphine)-1,1'-biphenyl were synthesized and used to prepare the ruthenium complex. The effects of para-substituted were observed, the results showed that the ruthenium catalysts [diphosphine RuCl2 diamine] containing both t-Bu and i-Pr substitutions have better activities and enantioselectivities than the non-substituted ruthenium catalysts in the asymmetric hydrogenation of acetophenone (C) 2010 Hua Chen Published by Elsevier B V. on behalf of Chinese Chemical Society All rights reserved

  DOI：

  10.1016/j.cclet.2010.01.030

文献信息

• <i>P</i>-Stereogenic Phosphines Directed Copper(I)-Catalyzed Enantioselective 1,3-Dipolar Cycloadditions
  作者：Zhenjie Gan、Mengna Zhi、Ruiping Han、Er-Qing Li、Zheng Duan、François Mathey

  DOI：10.1021/acs.orglett.9b00734

  日期：2019.4.19

  synthesized and used in the copper(I)-catalyzed enatioselective [3 + 2] cycloaddition of iminoesters with alkenes. A variety of highly functionalized pyrrolidines were obtained in excellent yield and enatioselectivity. This is the first example of a pair of P-stereogenic ligands working as pseudoenantiomers to tune the enantio- and diastereoselective 1,3-dipolar cycloaddition, and providing a pair of

  合成了一对新的具有多个手性中心的P-立体异构体，并将其用于亚铜与亚铜的亚铜酸酯的铜（I）催化对映选择性[3 + 2]环加成反应中。以优异的产率和对映选择性获得了各种高度官能化的吡咯烷。这是一对P-立体异构体作为假对映体的第一个例子，可调节对映体和非对映体选择性的1,3-偶极环加成，并分别提供一对对映体纯的吡咯烷。
• US5624788A
  申请人：——

  公开号：US5624788A

  公开（公告）日：1997-04-29
• US5773192A
  申请人：——

  公开号：US5773192A

  公开（公告）日：1998-06-30