4-(benzyloxymethyl)-1-phenyl-4-pentenol | 146060-63-1

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 4-(benzyloxymethyl)-1-phenyl-4-pentenol
• CAS: 146060-63-1
• 化学式: C₁₉H₂₂O₂
• 分子量: 282.382
• InChiKey: RVNWPNIXRPCQJX-UHFFFAOYSA-N

反应信息

• 作为产物：
  描述：

  氧化苯乙烯 、 2-benzyloxymethylallylmagnesium chloride 在 copper(l) iodide 作用下， 生成 4-(benzyloxymethyl)-1-phenyl-4-pentenol
  参考文献：
  名称：

  Addition of 2-(chloromagnesiomethyl)2-alkenyl ethers to epoxides followed by Pd(0)-catalyzed cyclization: a one-pot synthesis of 3-methylenetetrahydropyrans

  摘要：

  Addition of 2-(chloromagnesiomethyl)-2-propenyl ethers 1a and 1b to epoxides 3 affords ring opening products 6 or 7 which are converted by Pd(0) to 3-methylenetetrahydropyrans 9. Cyclization of the addition products is best effected by a catalyst system generated in situ from Pd(OAc)2 and (i-PrO)3P.

  DOI：

  10.1016/s0040-4020(01)92281-1