22-Hydroxy-N-[2-(5-hydroxy-1H-indol-3-YL)ethyl]docosanamide | 73956-49-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 英文名称: 22-Hydroxy-N-[2-(5-hydroxy-1H-indol-3-YL)ethyl]docosanamide
• CAS: 73956-49-7
• 化学式: C₃₂H₅₄N₂O₃
• 分子量: 514.8
• InChiKey: XWPKDSVRTTVLOJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  9.5
• 重原子数：
  37
• 可旋转键数：
  24
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.72
• 拓扑面积：
  85.4
• 氢给体数：
  4
• 氢受体数：
  3

文献信息

• Compounds, Compositions and Methods for Making the Same
  申请人：Vafai Scott

  公开号：US20090264496A1

  公开（公告）日：2009-10-22

  The present invention provides compounds and/or compositions that modulate PP2A methylation and/or activity and methods for preparing the same, which are useful for modulating the demethylation of PP2A, modulating the methylation of PP2A and/or modulating the activity of PP2A.

  本发明提供了能够调节PP2A甲基化和/或活性的化合物和/或组合物，以及制备这些化合物和/或组合物的方法。这些化合物和/或组合物可用于调节PP2A的去甲基化、甲基化和/或活性。
• Compounds, compositions and methods for making the same
  申请人：Signum Biosciences, Inc.

  公开号：US10583119B2

  公开（公告）日：2020-03-10

  The present invention provides compounds and/or compositions that modulate PP2A methylation and/or activity and methods for preparing the same, which are useful for modulating the demethylation of PP2A, modulating the methylation of PP2A and/or modulating the activity of PP2A.

  本发明提供了调节 PP2A 甲基化和/或活性的化合物和/或组合物以及制备方法，这些化合物和/或组合物可用于调节 PP2A 的去甲基化、调节 PP2A 的甲基化和/或调节 PP2A 的活性。
• COMPOUNDS, COMPOSITIONS AND METHODS FOR MAKING THE SAME
  申请人：Signum Biosciences, Inc.

  公开号：US20170266161A1

  公开（公告）日：2017-09-21

  The present invention provides compounds and/or compositions that modulate PP2A methylation and/or activity and methods for preparing the same, which are useful for modulating the demethylation of PP2A, modulating the methylation of PP2A and/or modulating the activity of PP2A.
• US9486441B2
  申请人：——

  公开号：US9486441B2

  公开（公告）日：2016-11-08
• [EN] COMPOUNDS, COMPOSITIONS AND METHODS FOR MAKING THE SAME<br/>[FR] COMPOSÉS, COMPOSITIONS ET PROCÉDÉS POUR PRÉPARER CEUX-CI
  申请人：SIGNUM BIOSCIENCES INC

  公开号：WO2009132051A1

  公开（公告）日：2009-10-29

  The present invention provides compounds and/or compositions that modulate PP2A methylation and/or activity and methods for preparing the same, which are useful for modulating the demethylation of PP2A, modulating the methylation of PP2 A and/or modulating the activity of PP2A.