{2-[6-(2-ethyl-5-fluoro-4-hydroxy-phenyl)-1H-indazole-3-yl]-1,4,6,7-tetrahydro-imidazo[4,5-c]pyridine-5-yl}-[5-(2-piperidine-1-yl-ethylamino)-pyrazine-2-yl]-methanone | 1421503-07-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 英文名称: {2-[6-(2-ethyl-5-fluoro-4-hydroxy-phenyl)-1H-indazole-3-yl]-1,4,6,7-tetrahydro-imidazo[4,5-c]pyridine-5-yl}-[5-(2-piperidine-1-yl-ethylamino)-pyrazine-2-yl]-methanone
• 英文别名: {2-[6-(2-ethyl-5-fluoro-4-hydroxy-phenyl)-1H-indazol-3-yl]-1,4,6,7-tetrahydroimidazolo[4,5-c]pyridin-5-yl}-[5-(2-piperidin-1-yl-ethylamino)-pyrazin-2-yl]-methanone；{2-[6-(2-ethyl-5-fluoro-4-hydroxy-phenyl)-1H-indazol-3-yl]-1,4,6,7-tetrahydro-imidazo[4,5-c]pyridin-5-yl}-[5-(2-piperidin-1-yl-ethylamino)-pyrazin-2-yl]-methanone；[2-[6-(2-ethyl-5-fluoro-4-hydroxyphenyl)-1H-indazol-3-yl]-3,4,6,7-tetrahydroimidazo[4,5-c]pyridin-5-yl]-[5-(2-piperidin-1-ylethylamino)pyrazin-2-yl]methanone
• CAS: 1421503-07-2
• 化学式: C₃₃H₃₆FN₉O₂
• 分子量: 609.706
• InChiKey: JRAGPXNFTHJRSY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4
• 重原子数：
  45
• 可旋转键数：
  8
• 环数：
  7.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  139
• 氢给体数：
  4
• 氢受体数：
  9

文献信息

• INDAZOLES
  申请人：Pfizer Limited

  公开号：EP2736907B1

  公开（公告）日：2015-10-07