N-Ethyl-3-methoxy-propionamide | 1340201-02-6

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: N-Ethyl-3-methoxy-propionamide
• 英文别名: N-ethyl-3-methoxypropanamide
• CAS: 1340201-02-6
• 化学式: C₆H₁₃NO₂
• 分子量: 131.17
• InChiKey: OYGDQLOTAHZZHD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.3
• 重原子数：
  9
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  38.3
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• SUBSTITUTED THIOPHENYL URACILS, SALTS THEREOF AND THE USE THEREOF AS HERBICIDAL AGENTS
  申请人：Syngenta Crop Protection AG

  公开号：US20210087151A1

  公开（公告）日：2021-03-25

  The invention relates to substituted thiophenyl uracils of general formula (I) or salts (I) thereof, wherein the groups in general formula (I) are as defined in the description, and to the use thereof as herbicides, in particular for controlling weeds and/or weed grasses in crops of cultivated plants and/or as plant growth regulators for influencing the growth of crops of cultivated plants.

  该发明涉及通式（I）的取代噻吩基尿嘧啶或其盐，其中通式（I）中的基团如描述中所定义，并且将其用作除草剂，特别是用于控制农作物中的杂草和/或杂草草本植物，或作为植物生长调节剂，以影响农作物的生长。
• PYRIDINYLQUINAZOLINAMINE DERIVATIVES AND THEIR USE AS B-RAF INHIBITORS
  申请人：Aquila Brian

  公开号：US20100216791A1

  公开（公告）日：2010-08-26

  The invention relates to chemical compounds of the formula (I) or pharmaceutically acceptable salts thereof, which possess B-Raf inhibitory activity and are accordingly useful for their anti cancer activity and thus in methods of treatment of the human or animal body. The invention also relates to processes for the manufacture of said chemical compounds, to pharmaceutical compositions containing them and to their use in the manufacture of medicaments of use in the production of an anti-cancer effect in a warm blooded animal such as man.

  本发明涉及化学式（I）的化合物或其药学上可接受的盐，其具有B-Raf抑制活性，因此在抗癌活性和人或动物体的治疗方法中有用。本发明还涉及制造所述化学化合物的过程，包含它们的制药组合物以及它们在制造用于产生温血动物（例如人）中的抗癌效应的药物中的使用。
• Substituted thiophenyl uracils, salts thereof and the use thereof as herbicidal agents
  申请人：Syngenta Crop Protection AG

  公开号：US11274083B2

  公开（公告）日：2022-03-15

  The invention relates to substituted thiophenyl uracils of general formula (I) or salts (I) thereof, wherein the groups in general formula (I) are as defined in the description, and to the use thereof as herbicides, in particular for controlling weeds and/or weed grasses in crops of cultivated plants and/or as plant growth regulators for influencing the growth of crops of cultivated plants.

  本发明涉及通式(I)的取代噻吩脲或其盐(I)，其中通式(I)中的基团如描述中所定义，并涉及其作为除草剂的用途，特别是用于控制栽培植物作物中的杂草和/或禾本科杂草和/或作为影响栽培植物作物生长的植物生长调节剂。
• [EN] PYRIDINYLQUINAZ0LINAMINE DERIVATIVES AND THEIR USE AS B-RAF INHIBITORS<br/>[FR] DÉRIVÉS DE PYRIDINYLQUINAZOLINAMINE ET LEUR UTILISATION COMME INHIBITEURS DE B-RAF
  申请人：ASTRAZENECA AB

  公开号：WO2008020203A1

  公开（公告）日：2008-02-21

  [EN] The invention relates to chemical compounds of the formula (I) or pharmaceutically acceptable salts thereof, which possess B-Raf inhibitory activity and are accordingly useful for their anti cancer activity and thus in methods of treatment of the human or animal body. The invention also relates to processes for the manufacture of said chemical compounds, to pharmaceutical compositions containing them and to their use in the manufacture of medicaments of use in the production of an anti-cancer effect in a warm blooded animal such as man.
  [FR] L'invention concerne des composés chimiques représentés par la formule (I) ou les sels pharmaceutiquement acceptables de ses composés, lesquels possèdent une activité inhibitrice de B-Raf et sont, en conséquence, utiles pour leur activité anti-cancer et, de ce fait, dans des procédés thérapeutiques chez l'humain ou l'animal. L'invention porte également sur des procédés de fabrication desdits composés chimiques, sur des compositions pharmaceutiques contenant lesdits composés chimiques et sur leur utilisation dans la fabrication de médicaments destinés à produire un effet anti-cancer chez un animal à sang chaud tel que l'homme.
• [EN] KINASE INHIBITOR COMPOUNDS<br/>[FR] COMPOSÉS INHIBITEURS DE KINASES
  申请人：XCOVERY INC

  公开号：WO2008033562A2

  公开（公告）日：2008-03-20

  [EN] The invention relates to compounds, compositions comprising the compounds, and methods of using the compounds and compound compositions. The compounds, compositions, and methods described herein can be used for the therapeutic modulation of kinase-mediated processes, and treatment of disease and disease symptoms, particularly those mediated by certain kinase enzymes.
  [FR] La présente invention concerne des composés, des compositions contenant lesdits composés, ainsi que des procédés d'utilisation desdits composés et desdites compositions. Les composés, les compositions, et les procédés faisant l'objet de la présente invention peuvent être utilisés pour la modulation thérapeutique de processus médiés par les kinases, ainsi que pour le traitement de maladies et de leurs symptômes, médiés en particulier par certaines enzymes de type kinase.