| 1239911-59-1

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• CAS: 1239911-59-1
• 化学式: C₂₀H₃₆O₃
• 分子量: 324.504
• InChiKey: IUCAYKCJLGEPSD-CAOOACKPSA-N

反应信息

• 作为产物：
  描述：

  、 异戊醛 在 锌 作用下， 以 四氢呋喃 为溶剂， 反应 2.0h， 以89%的产率得到
  参考文献：
  名称：

  Synthesis of two marine farnesylacetones that dilate the basilar arteries of rabbits

  摘要：

  We have synthesized novel vasodilatation farnesylacetones 1 and 2, which are major active constituents of Sargassum siliquastrum collected from the coast of the East Sea in Korea, in 9 steps. A test of the vasodilatation effect of synthetic intermediates and their deprotected compounds on the basilar arteries of rabbits revealed that 14 and 14-1 have a similar dilation effect as their target marine natural products 1 and 2. Crown Copyright (C) 2010 Published by Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmcl.2010.05.044