4,4'-双(2-氨基-6-甲基嘧啶基)硫醚 | 69945-13-7

• 物质功能分类: 医药中间体 - 杂环化合物 - 嘧啶类化合物
• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪类
• 中文名称: 4,4'-双(2-氨基-6-甲基嘧啶基)硫醚
• 中文别名: 4,4-双(2-氨基-6-甲苯嘧啶基)二硫化物
• 英文名称: 4,4'-bis(2-amino-6-methylpyrimidyl)disulfide
• 英文别名: 4,4'-Bis(2-amino-6-methylpyrimidyl)disulfid；6,6'-dimethyl-4,4'-disulfanediyl-bis-pyrimidin-2-ylamine；4-[(2-Amino-6-methylpyrimidin-4-yl)disulfanyl]-6-methylpyrimidin-2-amine
• CAS: 69945-13-7
• 化学式: C₁₀H₁₂N₆S₂
• 分子量: 280.377
• InChiKey: CLAPOZGLYFFUHA-UHFFFAOYSA-N

物化性质

• 熔点：
  208 °C

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  18
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  154
• 氢给体数：
  2
• 氢受体数：
  8

安全信息

• 海关编码：
  2933599090

反应信息

• 作为反应物：
  描述：

  、 4,4'-双(2-氨基-6-甲基嘧啶基)硫醚 在 solid supported PPh₃ 作用下， 以 苯 为溶剂， 反应 0.25h， 以45%的产率得到
  参考文献：
  名称：

  Biocatalytic Synthesis of Pikromycin, Methymycin, Neomethymycin, Novamethymycin, and Ketomethymycin

  摘要：

  A biocatalytic platform that employs the final two monomodular type I polyketide synthases of the pikromycin pathway in vitro followed by direct appendage of D-desosamine and final C-H oxidation(s) in vivo was developed and applied toward the synthesis of a suite of 12- and 14-membered ring macrolide natural products. This methodology delivered both compound classes in 13 steps (longest linear sequence) from commercially available (R)-Roche ester in >10% overall yields.

  DOI：

  10.1021/ja404134f

文献信息

• Ink composition and method of producing a processed product of printed matter
  申请人：FUJIFILM Corporation

  公开号：EP2302010A1

  公开（公告）日：2011-03-30

  An active radiation curable ink composition is disclosed. The ink composition includes a compound having a persulfide bond, at least one end of the persulfide bond being bonded to a ring structure directly or via a carbonyl group or a thiocarbonyl group; one or more radical polymerizable compounds; and a photopolymerization initiator.

  本发明公开了一种活性辐射固化油墨组合物。该油墨组合物包括一种具有过硫键的化合物，过硫键的至少一端直接或通过羰基或硫代羰基与环结构键合；一种或多种可自由基聚合的化合物；以及一种光聚合引发剂。
• LIQUID CRYSTAL ALIGNMENT SOLUTION
  申请人：Lai Ming-Chih

  公开号：US20090194737A1

  公开（公告）日：2009-08-06

  A liquid crystal alignment solution is provided. The liquid crystal alignment solution includes a first polyimide-polyamide acid and a second polyimide-polyamide acid. The first polyimide-polyamide acid is represented by formula (A), and the second polyimide-polyamide acid is represented by formula (B), in which T 1 , T 2 , T 3 and T 4 are each independently a tetravalent residue of a tetracarboxylic acid dianhydride; D 1 , D 2 , D 3 and D 4 are each independently a divalent residue of a diamine; and m, n, p and q are each independently an positive integer, wherein m/(m+n)≦0.5 and p/(p+q)≧0.5.
• INK COMPOSITION AND METHOD OF PRODUCING A PROCESSED PRODUCT OF PRINTED MATTER
  申请人：YOKOI Kazuhiro

  公开号：US20110074896A1

  公开（公告）日：2011-03-31

  An active radiation curable ink composition is disclosed. The ink composition includes a compound having a persulfide bond, at least one end of the persulfide bond being bonded to a ring structure directly or via a carbonyl group or a thiocarbonyl group; one or more radical polymerizable compounds; and a photopolymerization initiator.
• US7914863B2
  申请人：——

  公开号：US7914863B2

  公开（公告）日：2011-03-29
• US8449101B2
  申请人：——

  公开号：US8449101B2

  公开（公告）日：2013-05-28

表征谱图