4,4-(2-乙基-2-硝基三亚甲基)二吗啉 | 1854-23-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 恶嗪烷类
• 中文名称: 4,4-(2-乙基-2-硝基三亚甲基)二吗啉
• 英文名称: 4,4'-(2-Ethyl-2-nitrotrimethylene)dimorpholine
• 英文别名: 4-[2-(morpholin-4-ylmethyl)-2-nitrobutyl]morpholine
• CAS: 1854-23-5
• 化学式: C13H25N3O4
• 分子量: 287.36
• InChiKey: XPGDDCOXMUFUCB-UHFFFAOYSA-N

物化性质

• 沸点：
  349.65°C (rough estimate)
• 密度：
  1.135±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.1
• 重原子数：
  20
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  70.8
• 氢给体数：
  0
• 氢受体数：
  6

ADMET

毒理性

• 副作用

皮肤致敏剂 - 一种可以诱导皮肤产生过敏反应的制剂。

Skin Sensitizer - An agent that can induce an allergic reaction in the skin.

来源:Haz-Map, Information on Hazardous Chemicals and Occupational Diseases

反应信息

• 作为反应物：
  描述：

  4-(2-硝基丁基)吗啉 、 4,4-(2-乙基-2-硝基三亚甲基)二吗啉 以The P-1487 product produced when的产率得到Bioban P-1487
  参考文献：
  名称：

  Process for the production of non-lachrymatory nitro amines

  摘要：

  改进了从1-硝基丙烷、37%甲醛和吗啡啶反应生产P-1487的过程，其中改进包括在40°C至42°C的温度下混合1-硝基丙烷和37%甲醛，加入吗啡啶并保持温度在40°C至42°C，将混合物保持在40°C至42°C下两小时，冷却以允许分层，分离上层油层并通过去除多余的水浓缩油层以得到P-1487。

  公开号：

  US04088817A1

文献信息

• COLOR DEVELOPING COMPOSITION CONTAINING MOLECULAR COMPOUND, AND RECORDING MATERIAL
  申请人：Kodama Satoshi

  公开号：US20110120345A1

  公开（公告）日：2011-05-26

  Provided is a color-developing composition containing a molecular compound which has as a component compound a compound represented by formula (I) [wherein Y represents a C1-C12 hydrocarbon group which is chained or branched and saturated or unsaturated, or a C1-C8 hydrocarbon group which is chained or branched, saturated or unsaturated and has an ether or thioether bond; R 1 , R 2 , R 3 and R 4 each independently represent a C1-C6 alkyl group or C2-C6 alkenyl group; n, p, q and r each represents any integer of 0 to 4; and m represents any integer of 0 to 2]. Also provided is a recording material with a sufficient color-forming sensitivity, superior storage stability, and especially with an extremely little background fogging in a heat resistance test.

  提供的是一种含有分子化合物的彩色显影组合物，该分子化合物的组分包括由式（I）表示的化合物[其中Y表示链状或支链的C1-C12烃基，饱和或不饱和，或链状或支链的C1-C8烃基，饱和或不饱和，且具有醚或硫醚键；R1、R2、R3和R4各自独立地表示C1-C6烷基或C2-C6烯基；n、p、q和r各自表示0至4的任意整数；m表示0至2的任意整数]。还提供了一种具有足够的显色敏感性、优异的储存稳定性，特别是在耐热性测试中具有极少背景雾化的记录材料。
• ANTIMICROBIAL COMPOSITIONS COMPRISING TRIMETHYLENE GLYCOL OLIGOMER AND METHODS OF USING THE COMPOSITIONS
  申请人：Fenyvesi Gyorgyi

  公开号：US20110224307A1

  公开（公告）日：2011-09-15

  Disclosed are antimicrobial compositions, and methods for killing, inhibiting, or preventing the growth of microbes, using trimethylene glycol oligomers or dimers. The trimethylene glycol oligomers and dimers have the formula R(CH 2 CH 2 CH 2 —O—CH 2 CH 2 CH 2 ) n R 1 where R and R 1 are hydroxyl, amine, or ester functionalitiess, and n is 2 or higher. The antimicrobial compositions are useful in personal care and cosmetic compositions

  本发明涉及抗微生物组合物，以及使用三亚甲基二醇低聚物或二聚物杀灭、抑制或防止微生物生长的方法。所述三亚甲基二醇低聚物和二聚物的化学式为R(CH2CH2CH2—O—CH2CH2CH2)nR1，其中R和R1是羟基、胺基或酯基官能团，n为2或更高。所述抗微生物组合物适用于个人护理和化妆品组合物。
• Novel sulfur compounds and intermolecular compounds containing the same as the component compounds
  申请人：——

  公开号：US20030130358A1

  公开（公告）日：2003-07-10

  The invention aims at providing novel sulfur compounds, molecular compounds containing the same as the component compound, and so on. The above aim is achieved by using sulfur compounds of the general formula (I) wherein Rs are each independently hydrogen, optionally substituted C 1-6 alkyl, optionally substituted C 2-6 alkenyl, optionally substituted aryl, chloro, or bromo; m is an integer of 0, 1, or 2; and Z is a group represented by any of the general formulae (II) to (V) (wherein R and m are each as defined above; W is hydrogen or C 1-6 alkyl; and Y is a direct bond, C 1-3 alkylene, or phenylene). 1

  本发明旨在提供新型硫化合物、包含其作为组分化合物的分子化合物等。上述目的通过使用通式（I）的硫化合物实现，其中Rs分别独立地为氢、可选取代的C1-6烷基、可选取代的C2-6烯基、可选取代的芳基、氯或溴；m为0、1或2的整数；Z为由通式（II）至（V）中的任何一种表示的基团（其中R和m如上所定义；W为氢或C1-6烷基；Y为直接键、C1-3烷基或苯基）。
• Process for the production of 2-nitrobutylmorpholine
  申请人：International Minerals & Chemical Corp.

  公开号：US04140855A1

  公开（公告）日：1979-02-20

  In a process for the production of 2-nitrobutylmorpholine from 1-nitropropane, morpholine and formaldehyde the improvement comprising mixing 1-nitropropane and morpholine, heating to about 55-60.degree. C., adding formaldehyde over about a 3-4 hour period, holding the reaction mixture at about 55-60.degree. C. for about a 2-3 hour period to make a total addition/holding period of at least six hours, cooling the reacton mixture to form a two phase oil/aqueous system and concentrating the oil layer to 2-nitrobutylmorpholine by removing excess water and 1-nitropropane.

  从1-硝基丙烷，吗啡啶和甲醛制备2-硝基丁基吗啡啶的过程中，改进的方法包括混合1-硝基丙烷和吗啡啶，加热至约55-60°C，缓慢加入甲醛约3-4小时，将反应混合物保持在约55-60°C下约2-3小时，使总加入/保持时间至少为6小时，冷却反应混合物以形成两相油/水系统，并通过去除多余的水和1-硝基丙烷将油层浓缩为2-硝基丁基吗啡啶。
• Molecular Healing of Polymeric Materials, Coatings, Plastics, Elastomers, Composites, Laminates, Adhesives, and Sealants by Active Enzymes
  申请人：McDaniel C. Steven

  公开号：US20100210745A1

  公开（公告）日：2010-08-19

  Disclosed herein are polymeric materials such as a coating, a plastic, a laminate, a composite, an elastomer, an adhesive, or a sealant; a surface treatment such as a textile finish or a wax; a filler for such a polymeric material or a surface treatment that includes an enzyme such as an esterase (e.g., a lipolytic enzyme, a sulfuric ester hydrolase, an organophosphorus compound degradation enzyme), an enzyme (e.g., a lysozyme, a lytic transglycosylase) that degrades a cell wall and/or a cell membrane component, a biocidal or biostatic peotide, and/or a peptidase. Also disclosed herein are methods of altering a material's property such as service life, flexability, or rigidity, by incorporation of an enzyme into a material capable of being chemically crosslinked by the activity of a lipolytic enzyme, a hydrolase, and/or a urease.

  本文公开了一些聚合材料，如涂层、塑料、层压板、复合材料、弹性体、粘合剂或密封剂；一种表面处理，如纺织品涂层或蜡；一种填料，用于这样的聚合材料或表面处理，其中包括一种酶，如酯酶（例如，脂肪水解酶，硫酸酯水解酶，有机磷化合物降解酶），降解细胞壁和/或细胞膜成分的酶（例如，溶菌酶，裂解转糖基酶），生物杀菌或生物静态肽，以及/或肽酶。本文还公开了通过将酶纳入可通过脂肪水解酶、水解酶和/或脲酶的活性交联材料中来改变材料性能，如使用寿命、柔韧性或刚度的方法。