4H-Indol-4-one, 1,5,6,7-tetrahydro-1-(1-methylethyl)- | 1251256-17-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 英文名称: 4H-Indol-4-one, 1,5,6,7-tetrahydro-1-(1-methylethyl)-
• 英文别名: 1-propan-2-yl-6,7-dihydro-5H-indol-4-one
• CAS: 1251256-17-3
• 化学式: C₁₁H₁₅NO
• 分子量: 177.24
• InChiKey: FDCWGNZUIHTRBU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  13
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.55
• 拓扑面积：
  22
• 氢给体数：
  0
• 氢受体数：
  1

文献信息

• SUBSTITUTED DIMETHYLCYCLOBUTYL COMPOUNDS, THEIR PREPARATION AND USE IN MEDICAMENTS
  申请人：Cuberes Altisent Maria Rosa

  公开号：US20100105680A1

  公开（公告）日：2010-04-29

  The present invention relates to substituted dimethylcyclobutyl compounds of general formula I, a process for their preparation, medicaments comprising said substituted dimethylcyclobutyl compounds as well as the use of said substituted dimethylcyclobutyl compounds for the preparation of medicaments, which are particularly suitable for the prophylaxis and/or treatment of disorders or diseases that are at least partially mediated via sigma receptors.

  本发明涉及通式I的取代二甲基环丁基化合物，其制备方法，包含所述取代二甲基环丁基化合物的药物以及使用所述取代二甲基环丁基化合物制备药物，特别适用于预防和/或治疗至少部分通过sigma受体介导的疾病或疾病的药物。