6-Oxa-dodecandisaeure | 7735-08-2

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 6-Oxa-dodecandisaeure
• 英文别名: 6-Oxa-dodecandicarbonsaeure；6-(4-Carboxybutoxy)hexanoic acid
• CAS: 7735-08-2
• 化学式: C₁₁H₂₀O₅
• 分子量: 232.277
• InChiKey: ZUSNAHBJUTXIQK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.9
• 重原子数：
  16
• 可旋转键数：
  11
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.82
• 拓扑面积：
  83.8
• 氢给体数：
  2
• 氢受体数：
  5

文献信息

• Synthetic absorbable surgical devices of polyester amides and process for making them
  申请人：MINNESOTA MINING AND MANUFACTURING COMPANY

  公开号：EP0030822A2

  公开（公告）日：1981-06-24

  A body-absorbable polymeric material for surgical implantation which is a condensation product of reacting a diamine with lactic or glycolic acid to form a diamidediol which is then reacted with a bischloroformate or a compound selected from the group consisting of dicarboxylic acids, methyl and ethyl esters of dicarboxylic acids, diacidchlorides, and anhydrides of a dicarboxylic acid. The polymeric material has a high degree of softness and flexibility and it is useful as synthetic absorbable surgical sutures.

  一种可被人体吸收的外科植入用聚合材料，它是二胺与乳酸或乙醇酸反应生成二亚硫酸的缩合产物，二亚硫酸再与双氯甲酸酯或选自二羧酸、二羧酸甲酯和乙酯、二酸氯化物和二羧酸酸酐组成的化合物反应生成。这种聚合物材料具有高度的柔软性和弹性，可用作合成可吸收手术缝合线。
• Biodegradable polymeric materials based on polyether glycols, processes for the preparation thereof and surgical articles made therefrom
  申请人：BIOMEDICAL POLYMERS INTERNATIONAL, LTD.

  公开号：EP0295055A2

  公开（公告）日：1988-12-14

  The invention provides poly(α-hydroxy-carboxylic acid)/­poly(oxyalkylene) polymers selected from multiblock polymers of the following repeating unit I wherein R is an alkylene group, R₁ is hydrogen or methyl groups, m is a positive integer, and a and b are zero or positive integers, the case where a and b are simultaneously zero being excluded, and chain extended multiblock polymers which polymers are bioabsorbable and biodegradable, these polymeric materials being derived from reacting diols in the form of polyether glycols with α-hydroxy-carboxylic acids. The invention also provides methods for the preparation of such polymeric materials and bioabsorbable surgical articles made therefrom.

  本发明提供的聚(α-羟基-羧酸)/聚(氧亚烷基)聚合物选自以下重复单元 I 的多嵌段聚合物 其中 R 为亚烷基，R₁ 为氢或甲基，m 为正整数，a 和 b 为零或正整数，不包括 a 和 b 同时为零的情况；以及链延伸多嵌段聚合物，这些聚合物具有生物可吸收性和生物可降解性，这些聚合物材料由聚醚二醇形式的二醇与α-羟基羧酸反应而得。本发明还提供了制备这种聚合材料和由其制成的生物可吸收外科用品的方法。
• Polyurethane-based polymeric materials and biomedical articles and pharmaceutical compositions utilizing the same
  申请人：BIOMEDICAL POLYMERS INTERNATIONAL, LTD.

  公开号：EP0396429B1

  公开（公告）日：1996-07-31
• PROCESS FOR INCREASING STABILITY OF POLY(ESTERAMIDES)
  申请人：MINNESOTA MINING AND MANUFACTURING COMPANY

  公开号：EP0621881A1

  公开（公告）日：1994-11-02
• EP0960148A4
  申请人：——

  公开号：EP0960148A4

  公开（公告）日：2000-03-08