| 1160183-84-5

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• CAS: 1160183-84-5
• 化学式: C₁₅H₂₀O₃
• 分子量: 248.322
• InChiKey: NHSXSLSZNBCNIV-AWEZNQCLSA-N

反应信息

• 作为反应物：
  描述：

  在 sodium tetrahydroborate 、 cerium(III) chloride 作用下， 以 乙醇 为溶剂， 反应 0.33h， 以72%的产率得到
  参考文献：
  名称：

  Novel megastigmanes with lipid accumulation inhibitory and lipid metabolism-promoting activities in HepG2 cells from Sedum sarmentosum

  摘要：

  Four novel megastigmanes, neosedumosides I (1), II (2), III(3), and IV (4) were isolated from the whole plant of Sedum sarmentosum (Crassulaceae). Absolute stereostructures of these constituents were determined on the basis of chemical and physicochemical evidence. Among them, 1-3 were found to show lipid accumulation inhibitory activity in HepG2 cells. Furthermore, 2 and 3 were found to also show lipid metabolism-promoting activity. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2009.03.040
• 作为产物：
  描述：

  neosarmentol III 、 乙酸酐 在 吡啶 作用下， 反应 18.0h， 以90%的产率得到
  参考文献：
  名称：

  Novel megastigmanes with lipid accumulation inhibitory and lipid metabolism-promoting activities in HepG2 cells from Sedum sarmentosum

  摘要：

  Four novel megastigmanes, neosedumosides I (1), II (2), III(3), and IV (4) were isolated from the whole plant of Sedum sarmentosum (Crassulaceae). Absolute stereostructures of these constituents were determined on the basis of chemical and physicochemical evidence. Among them, 1-3 were found to show lipid accumulation inhibitory activity in HepG2 cells. Furthermore, 2 and 3 were found to also show lipid metabolism-promoting activity. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2009.03.040