| 1393661-20-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• CAS: 1393661-20-5
• 化学式: C₁₁H₁₁NO₃
• 分子量: 205.213
• InChiKey: QBHOLMYFYKHCTR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.73
• 重原子数：
  15.0
• 可旋转键数：
  3.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.27
• 拓扑面积：
  55.4
• 氢给体数：
  1.0
• 氢受体数：
  3.0

反应信息

• 作为产物：
  描述：

  马来酰亚胺 、 苯氧乙酸 在 dioxide titanium 作用下， 以 乙腈 为溶剂， 反应 17.0h， 以31%的产率得到
  参考文献：
  名称：

  Unconventional Titania Photocatalysis: Direct Deployment of Carboxylic Acids in Alkylations and Annulations

  摘要：

  Under dry, anaerobic conditions, TiO2 photocatalysis of carboxylic add precursors resulted in carbon-carbon bond-forming processes. High yields of dirners were obtained from TiO2 treatment of carboxylic acids alone: On inclusion of electron-deficient alkenes, efficient alkylations were achieved with methoxymethyl and phenoxymethyl radicals. In reactions with maleic anhydride or maleimides, phenoxyacetic acid produced chromenedione derivatives in addition to adducts. These photocatalytic reactions are simple and cheap to perform, and the TiO2 is easily removed by filtration. The anaerobic photocatalysis strategy offers a range of synthetic possibilities.

  DOI：

  10.1021/ja306168h

文献信息

• Photocatalytic Conversion of Lignin Models into Functionalized Aromatic Molecules Initiated by the Proton-Coupled Electron Transfer Process
  作者：Yi Li、Jingya Wen、Simeng Wu、Sha Luo、Chunhui Ma、Shujun Li、Zhijun Chen、Shouxin Liu、Bing Tian

  DOI：10.1021/acs.orglett.4c00026

  日期：2024.2.16

  achieved via photocatalysis. This protocol exhibits a broad scope of lignin models and excellent compatibility of functionalization reagents, constructing a series of functionalized lignin-based aromatic compounds. Highly selective formation of alkyl radical species through a proton-coupled electron transfer and β-scission process provides the opportunity to form new C–C and C–N bonds by reaction with

  通过光催化实现了一种温和有效的木质素 β-O-4 裂解和功能化方法。该方案展示了广泛的木质素模型和功能化试剂的良好兼容性，构建了一系列功能化的木质素基芳香族化合物。通过质子耦合电子转移和β-断裂过程高度选择性地形成烷基自由基物种，提供了通过与亲电试剂反应形成新的C-C和C-N键的机会。