1-Ethyl-2-indanone | 91142-27-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 茚满类
• 英文名称: 1-Ethyl-2-indanone
• 英文别名: 1-Ethyl-indan-2-on；1-Aethyl-indan-2-on；1-Ethyl-1,3-dihydroinden-2-one
• CAS: 91142-27-7
• 化学式: C₁₁H₁₂O
• 分子量: 160.216
• InChiKey: ARVZHNOQGGTQSX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  12
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  1-Ethyl-2-indanone 在 chromium(VI) oxide 、 硫酸 作用下， 生成 2-(2-propionylphenyl)acetic acid
  参考文献：
  名称：

  Olsman,H. et al., Recueil des Travaux Chimiques des Pays-Bas, 1964, vol. 83, p. 301 - 306

  摘要：

  DOI：
• 作为产物：
  描述：

  3-乙基-1H-茚 在 sodium dichromate 、 硼烷四氢呋喃络合物 、 硫酸 作用下， 生成 1-Ethyl-2-indanone
  参考文献：
  名称：

  Hydroborations: A New Efficient Route to 1-Organo-2-indanones from 1-Alkyl(aryl)indenes

  摘要：

  在 1-烷基-1-茚和 1-芳基-1-茚的情况下，先进行氢硼化反应，然后再进行铬酸氧化反应，可以得到相应的 1-有机-2-茚酮，收率为 70-80%。

  DOI：

  10.1055/s-1990-27023

文献信息

• Novel synthesis of phenol derivatives by palladium-catalyzed cyclocarbonylation of 2,4-pentadienyl acetates
  作者：Youichi Ishii、Chao Gao、Wen Xiang Xu、Masakazu Iwasaki、Masanobu Hidai

  DOI：10.1021/jo00076a051

  日期：1993.11

  Phenyl acetates were selectively obtained in good yields by cyclocarbonylation of 2,4-pentadienyl acetates in the presence of NEt3, Ac2O, and a catalytic amount of palladium complexes such as PdCl2(PPh3)2 at 120-140-degrees-C under 50 atm of CO. No five-membered ring products were observed. A platinum complex PtCl2(PPh3)2 was also effective as a catalyst. The reaction of 5-phenyl-2,4-pentadienyl bromide with M(CO)(PPh3)3 (M = Pd or Pt) under CO gave the corresponding 6-phenyl-3, 5-hexadienoyl complexes in a high yield, which in turn afforded 2-acetoxybiphenyl in 41-51% yield on heating to 160-degrees-C under 50 atm of CO in the presence of NEt3 and Ac2O. Similar 3,5-hexadienoyl complexes are proposed to be intermediates in the catalytic cyclocarbonylation of 2,4-pentadienyl acetates. On the other hand, PdCl2(PPh3)2-catalyzed carbonylation of o-(bromomethyl)(1-alkenyl)-benzenes in the presence of NEt3 and Ac2O gave 2-naphthyl acetates in moderate yields, while the reaction in the absence of Ac2O gave five-membered ring products such as 2-indanones or a tricyclic lactone by incorporation of one or two CO molecules, respectively.
• KIRKIACHARIAN, B. S.;KOUTSOURAKIS, P. G., SYNTHESIS (BRD),(1990) N, C. 815-816
  作者：KIRKIACHARIAN, B. S.、KOUTSOURAKIS, P. G.

  DOI：——

  日期：——