4-(2-methoxycarbonyl-ethyl)-nonanedioic acid dimethyl ester | 58819-52-6

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 4-(2-methoxycarbonyl-ethyl)-nonanedioic acid dimethyl ester
• 英文别名: 4-(2-Methoxycarbonyl-aethyl)-nonandisaeure-dimethylester；Dimethyl 4-(3-methoxy-3-oxopropyl)nonanedioate
• CAS: 58819-52-6
• 化学式: C₁₅H₂₆O₆
• 分子量: 302.368
• InChiKey: YKMFXFSZXSNRCB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  21
• 可旋转键数：
  14
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  78.9
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  邻苯二甲醚 、 4-(2-methoxycarbonyl-ethyl)-nonanedioic acid dimethyl ester 生成 4-<3-Amino-3-(3,4-dimethoxyphenyl)propyl>-1,9-bis-(3,4-dimethoxyphenyl)-1,9-nonandiamin
  参考文献：
  名称：

  Alkylenepoly(aralkylamines) and the salts thereof

  摘要：

  新型的烷基聚（芳基胺）和相关化合物，其药学上可接受的酸盐加成物以及含有这些物质的组合物已被发现在哺乳动物中表现出高持续和有用的纤溶活性。

  公开号：

  US03929887A1
• 作为产物：
  描述：

  4-(2-ethoxycarbonyl-ethyl)-5-oxo-nonanedioic acid diethyl ester 在 sodium hydroxide 、 一水合肼 、 二乙二醇 作用下， 生成 4-(2-methoxycarbonyl-ethyl)-nonanedioic acid dimethyl ester
  参考文献：
  名称：

  The relative formation ages of ferromagnesian chondrules inferred from their initial aluminum-26/aluminum-27 ratios

  摘要：

  Abstract— We performed a systematic high‐precision secondary ion mass spectrometry 26Al‐26Mg isotopic study for 11 ferromagnesian chondrules from the highly unequilibrated ordinary chondrite Bishunpur (LL3.1). The chondrules are porphyritic and contain various amounts of olivine and pyroxene and interstitial plagioclase and/or glass. The chemical compositions of the chondrules vary from FeO‐poor to FeO‐rich. Eight chondrules show resolvable 26Mg excesses with a maximum δ26Mg of ˜1% in two chondrules. The initial 26Al/27Al ratios inferred for these chondrules range between (2.28 ± 0.73) × 10−5 to (0.45 ± 0.21) × 10−5. Assuming a homogeneous distribution of Al isotopes in the early solar system, this range corresponds to ages relative to CAIs between 0.7 ± 0.2 Ma and 2.4+0.7−0.4 Ma. The inferred total span of the chondrule formation ages is at least 1 Ma, which is too long to form chondrules by the X‐wind. The initial 26Al/27Al ratios of the chondrules are found to correlate with the proportion of olivine to pyroxene suggesting that olivine‐rich chondrules formed earlier than pyroxene‐rich chondrules. Though we do not have a completely satisfactory explanation of this correlation we tentatively interpret it as a result of evaporative loss of Si from earlier generations of chondrules followed by addition of Si to the precursors of later generation chondrules.

  DOI：

  10.1111/j.1945-5100.2002.tb00825.x

文献信息

• US4107165A
  申请人：——

  公开号：US4107165A

  公开（公告）日：1978-08-15
• The relative formation ages of ferromagnesian chondrules inferred from their initial aluminum-26/aluminum-27 ratios
  作者：Smail Mostefaoui、Noriko T. Kita、Shigeko Togashi、Shogo Tachibana、Hiroko Nagahara、Yuichi Morishita

  DOI：10.1111/j.1945-5100.2002.tb00825.x

  日期：2002.3

  Abstract— We performed a systematic high‐precision secondary ion mass spectrometry 26Al‐26Mg isotopic study for 11 ferromagnesian chondrules from the highly unequilibrated ordinary chondrite Bishunpur (LL3.1). The chondrules are porphyritic and contain various amounts of olivine and pyroxene and interstitial plagioclase and/or glass. The chemical compositions of the chondrules vary from FeO‐poor to FeO‐rich. Eight chondrules show resolvable 26Mg excesses with a maximum δ26Mg of ˜1% in two chondrules. The initial 26Al/27Al ratios inferred for these chondrules range between (2.28 ± 0.73) × 10−5 to (0.45 ± 0.21) × 10−5. Assuming a homogeneous distribution of Al isotopes in the early solar system, this range corresponds to ages relative to CAIs between 0.7 ± 0.2 Ma and 2.4+0.7−0.4 Ma. The inferred total span of the chondrule formation ages is at least 1 Ma, which is too long to form chondrules by the X‐wind. The initial 26Al/27Al ratios of the chondrules are found to correlate with the proportion of olivine to pyroxene suggesting that olivine‐rich chondrules formed earlier than pyroxene‐rich chondrules. Though we do not have a completely satisfactory explanation of this correlation we tentatively interpret it as a result of evaporative loss of Si from earlier generations of chondrules followed by addition of Si to the precursors of later generation chondrules.
• Alkylenepoly(aralkylamines) and the salts thereof
  申请人：ENDO LABORATORIES INC.

  公开号：US03929887A1

  公开（公告）日：1975-12-30

  Novel alkylenepoly(aralkylamines) and related compounds, the pharmaceutically acceptable acid addition salts thereof and compositions containing such substances have been found to exhibit high sustained and useful levels of fibrinolytic acitivity in mammals.

  新型的烷基聚（芳基胺）和相关化合物，其药学上可接受的酸盐加成物以及含有这些物质的组合物已被发现在哺乳动物中表现出高持续和有用的纤溶活性。