申请人:Lubrizol Advanced Materials, Inc.
公开号:US10023738B2
公开(公告)日:2018-07-17
The invention provides a bioabsorbable blend of (i) a polymer component comprising polylactic acid (PLA), polyglycolic acid (PGA), a copolymer of PLA and PGA, or any combination thereof and (ii) thermoplastic polyurethane (TPU) tailored to a medical application, and a process for making the same. In some embodiments, the TPU comprises units derived from a diol chain extender, a diisocyanate, and a polyol formulated to provide a set biodegradation rate in combination with at least one physical property. The blend of the invention provides useful materials for medical applications that have the individual benefits of polylactic acid and TPU while moderating each material's typical limitations.
本发明提供了一种生物可吸收混合物,该混合物包含(i)由聚乳酸(PLA)、聚乙醇酸(PGA)、PLA 和 PGA 的共聚物或其任意组合组成的聚合物成分和(ii)专为医疗应用定制的热塑性聚氨酯(TPU),以及制造该混合物的工艺。在某些实施例中,热塑性聚氨酯包括由二元醇扩链剂、二异氰酸酯和多元醇衍生的单元,其配制目的是结合至少一种物理特性提供设定的生物降解率。本发明的混合物为医疗应用提供了有用的材料,既具有聚乳酸和热塑性聚氨酯的各自优点,又缓和了每种材料的典型局限性。