Ethoxycarbonylmethyl-(1-isopropenyl-4-methylene-hex-5-enyl)-dimethyl-ammonium; bromide | 138054-44-1

• 分子结构分类: 有机化合物
• 英文名称: Ethoxycarbonylmethyl-(1-isopropenyl-4-methylene-hex-5-enyl)-dimethyl-ammonium; bromide
• CAS: 138054-44-1
• 化学式: Br*C₁₆H₂₈NO₂
• 分子量: 346.308
• InChiKey: JEHADQXKVJSSBK-UHFFFAOYSA-M

反应信息

• 作为反应物：
  描述：

  Ethoxycarbonylmethyl-(1-isopropenyl-4-methylene-hex-5-enyl)-dimethyl-ammonium; bromide 在 potassium tert-butylate 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 2.0h， 以84%的产率得到(E)-2-Dimethylamino-4-methyl-8-methylene-deca-4,9-dienoic acid ethyl ester
  参考文献：
  名称：

  Stereoselective synthesis of trisubstituted Z- or E-olefins employing N-substituted .beta.-methallyldimethylammonium ylides

  摘要：

  [2,3] Sigmatropic rearrangement of N-substituted beta-methallyldimethylammonium ylides forms tri-substituted olefins with high stereoselectivity. Ylides with a powerful electron-withdrawing substituent (-COCH3 or -CO2Et) in the alpha-position and those with a vinyl group carrying an ester moiety at the beta-position afford exclusively E- and Z-olefins, respectively.

  DOI：

  10.1021/jo00028a006