methyl 16-mercaptohexadecanoate | 124536-81-8

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: methyl 16-mercaptohexadecanoate
• 英文别名: Methyl 16-sulfanylhexadecanoate
• CAS: 124536-81-8
• 化学式: C₁₇H₃₄O₂S
• 分子量: 302.522
• InChiKey: QRSZRBGLKUGJGQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.8
• 重原子数：
  20
• 可旋转键数：
  16
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.94
• 拓扑面积：
  27.3
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  2-cyanobenzo[d]thiazol-6-yl 3-(pyridin-2-yldisulfanyl)propyl carbonate 、 methyl 16-mercaptohexadecanoate 在 三乙胺 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 2.0h， 生成 methyl 16-((3-((2-cyanobenzo[d]thiazol-6-yloxy)carbonyloxy)propyl)disulfanyl)hexadecanoate
  参考文献：
  名称：

  Compositions and Methods for in Vivo Imaging

  摘要：

  本公开提供了脂质探针化合物和含有这些化合物的组合物。一种脂质探针化合物可用于各种成像应用，也提供了这些应用。

  公开号：

  US20140199239A1

文献信息

• COMPOSITIONS AND METHODS FOR IN VIVO IMAGING
  申请人：The Regents of the University of California

  公开号：US20150343094A1

  公开（公告）日：2015-12-03

  The present disclosure provides lipid-probe compounds, and compositions comprising the compounds. A subject lipid-probe compound is useful for various imaging applications, which are also provided.

  本公开提供脂质探针化合物和包含该化合物的组合物。所述脂质探针化合物对于各种成像应用非常有用，该应用也提供了。
• Compositions and methods for in vivo imaging
  申请人：The Regents of the University of California

  公开号：US10010629B2

  公开（公告）日：2018-07-03

  The present disclosure provides lipid-probe compounds, and compositions comprising the compounds. A subject lipid-probe compound is useful for various imaging applications, which are also provided.

  本公开提供了脂质探针化合物以及包含该化合物的组合物。所涉及的脂质探针化合物可用于各种成像应用，这些应用也已提供。
• SENSING SURFACES CAPABLE OF SELECTIVE BIOMOLECULAR INTERACTIONS, TO BE USED IN BIOSENSOR SYSTEMS
  申请人：Pharmacia Biosensor AB

  公开号：EP0589867A1

  公开（公告）日：1994-04-06
• Asymmetrically Functionalized NanoParticles
  申请人：Shumaker-Parry Jennifer S.

  公开号：US20090256116A1

  公开（公告）日：2009-10-15

  The invention provides methods and compositions having at least one asymmetrically functionalized nanoparticle. An asymmetrically functionalized nanoparticle can comprise a nanoparticle core having an outer surface, a primary group of first ligands attached to a substantially continuous primary region of the outer surface, and a secondary group of second ligands attached to a substantially continuous secondary region of the outer surface, such that the primary group of first ligands and the secondary group of second ligands comprise a different ligand population.
• METHODS FOR SELECTING ENZYMES HAVING ENHANCED ACTIVITY
  申请人：NOVOZYMES A/S

  公开号：US20180073017A1

  公开（公告）日：2018-03-15

  Provided herein are methods and means for enhancing enzymatic activity. The system makes use of an emulsion for in vitro compartmentalization of a library of synthetic compounds which have a gene and a marked enzymatic substrate both directly linked to a solid phase. Expressed enzymes with greater activity will preferentially release the selectable marker from the solid phase, whereas enzymes with less activity will leave the markers intact. Removal of the marked compounds provides an enriched gene library encoding for more active variants. Also described are synthetic compounds and emulsions which can be used in the methods.