| 1312942-24-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡喃二恶英
• CAS: 1312942-24-7
• 化学式: C₂₉H₂₆F₆N₂O₅S
• 分子量: 628.592
• InChiKey: ZTDGNEKDGZKGDZ-FTEXIELVSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.8
• 重原子数：
  43.0
• 可旋转键数：
  6.0
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.34
• 拓扑面积：
  81.21
• 氢给体数：
  3.0
• 氢受体数：
  6.0

反应信息

• 作为产物：
  描述：

  benzyl 4,6-O-benzylidene-2-amino-2-deoxy-α-D-glucopyranoside 、 3,5-双(三氟甲基)苯基异硫氰酯 以 二氯甲烷 为溶剂， 反应 2.5h， 以92%的产率得到
  参考文献：
  名称：

  Carbohydrate-derived alcohols as organocatalysts in enantioselective aldol reactions of isatins with ketones

  摘要：

  The catalytic activity of carbohydrate-derived amino alcohols in the enantioselective aldol reaction of ketones with isatin and its derivatives has been examined for the first time. The carbohydrate-derived amino alcohols 5 were found to be efficient organocatalysts for asymmetric aldol reactions. A variety of isatins were used as substrates and the corresponding aldol products were obtained in high yields (up to 99%) and with moderate enantioselectivities (up to 75%). Crown Copyright (C) 2011 Published by Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetasy.2011.04.007