(2R,3S,4R,5S)-3,4,5-trihydroxy-1-(4'-methoxybenzenesulfonyl)-piperidine-2-carboxylic acid benzyl ester | 642089-98-3

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: (2R,3S,4R,5S)-3,4,5-trihydroxy-1-(4'-methoxybenzenesulfonyl)-piperidine-2-carboxylic acid benzyl ester
• 英文别名: benzyl (2R,3S,4R,5S)-3,4,5-trihydroxy-1-(4-methoxyphenyl)sulfonylpiperidine-2-carboxylate
• CAS: 642089-98-3
• 化学式: C₂₀H₂₃NO₈S
• 分子量: 437.471
• InChiKey: GYSWFPKUVDKCIK-MANSERQUSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1
• 重原子数：
  30
• 可旋转键数：
  7
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.35
• 拓扑面积：
  142
• 氢给体数：
  3
• 氢受体数：
  9

反应信息

• 作为反应物：
  描述：

  (2R,3S,4R,5S)-3,4,5-trihydroxy-1-(4'-methoxybenzenesulfonyl)-piperidine-2-carboxylic acid benzyl ester 、 2,2-二甲氧基丙烷 在 对甲苯磺酸 作用下， 以 DMF (N,N-dimethyl-formamide) 为溶剂， 生成 (3aS,4R,7S,7aR)-7-hydroxy-5-(4'-methoxybenzenesulfonyl)-2,2-dimethyl-hexahydro-[1,3]dioxolo[4,5-c]pyridine-4-carboxylic acid benzyl ester
  参考文献：
  名称：

  EP1516872

  摘要：

  公开号：
• 作为产物：
  描述：

  (3aS,6R,7S,7aS)-5-(4'-methoxybenzenesulfonyl)-2,2-dimethyl-7-(tetrahydropyranyloxy)-hexahydro-[1,3]dioxolo[4,5-c]pyridine-6-carboxylic acid benzyl ester 在 a cation exchange resin (Muromac) 作用下， 以 甲醇 为溶剂， 生成 (2R,3S,4R,5S)-3,4,5-trihydroxy-1-(4'-methoxybenzenesulfonyl)-piperidine-2-carboxylic acid benzyl ester
  参考文献：
  名称：

  EP1516872

  摘要：

  公开号：

文献信息

• Novel azasugar derivative and drug containing the same as the active ingredient
  申请人：Tsukida Takahiro

  公开号：US20050137221A1

  公开（公告）日：2005-06-23

  A novel azasugar derivative, and a drug containing the same as an active ingredient are disclosed. The drug is useful for treatment of keratinocyte-proliferative diseases.

  本发明揭示了一种新型的氮杂糖衍生物以及含有该衍生物作为活性成分的药物。该药物可用于治疗角质形成细胞增殖性疾病。
• Azasugar derivative and drug containing the same as the active ingredient
  申请人：Carna Biosciences Inc.

  公开号：US07223779B2

  公开（公告）日：2007-05-29

  A novel azasugar derivative, and a drug containing the same as an active ingredient are disclosed. The drug is useful for treatment of keratinocyte-proliferative diseases.

  本发明揭示了一种新的氮杂糖衍生物，以及包含该衍生物作为活性成分的药物。该药物可用于治疗角质形成细胞增殖性疾病。
• NOVEL ACRYLATES, NOVEL ALLYL ETHERS, NOVEL ALLYL CARBONATES, ACRYLATE POLYMERS, ALLYL ETHER POLYMERS, ALLYL CARBONATE POLYMERS, AND SOLID POLYELECTROLYTES
  申请人：MITSUI PETROCHEMICAL INDUSTRIES, LTD.

  公开号：EP0787749A1

  公开（公告）日：1997-08-06

  The novel acrylic ester, allyl ether and allyl carbonate of the present invention are characterized by having the structures represented by the following general formulae (I) to (IV): The above acrylic ester, allyl ether and allyl carbonate are used as a starting monomer which forms a polymer matrix for use in a polymeric solid electrolyte. The novel polymer of the present invention comprises structural units derived from at least one compound selected from a group of the compounds represented by the above general formulae (I) to (IV). The polymeric solid electrolyte comprising the above novel polymer as a polymer matrix exhibits high ionic conductivity and is chemically stable. The polymeric solid electrolyte comprising the above novel polymer as a matrix exhibits high ionic conductivity and is electrochemically stable, so that it can be used in, for example, an electrochemical element such as a primary battery, a secondary battery, a capacitor or an electrochromic display and a medical actuator.

  本发明的新型丙烯酸酯、烯丙基醚和碳酸烯丙基酯的特点是具有以下通式 (I) 至 (IV) 所代表的结构： 上述丙烯酸酯、烯丙基醚和碳酸烯丙基酯用作起始单体，形成聚合物基体，用于聚合固体电解质。 本发明的新型聚合物由至少一种从上述通式（I）至（IV）所代表的化合物组中选出的化合物衍生的结构单元组成。由上述新型聚合物作为聚合物基质的聚合物固体电解质具有高离子电导率和化学稳定性。 以上述新型聚合物为基质的聚合物固体电解质具有高离子导电性和电化学稳定性，因此可用于电化学元件，例如一次电池、二次电池、电容器或电致变色显示器和医疗致动器。
• NOVEL AZASUGAR DERIVATIVE AND DRUG CONTAINING THE SAME AS THE ACTIVE INGREDIENT
  申请人：Carna Biosciences Inc.

  公开号：EP1516872A1

  公开（公告）日：2005-03-23

  A novel azasugar derivative, and a drug containing the same as an active ingredient are disclosed. The drug is useful for treatment of keratinocyte-proliferative diseases.

  本发明公开了一种新型天苏糖衍生物和一种含有天苏糖衍生物作为活性成分的药物。该药物可用于治疗角质细胞增生性疾病。
• NOVEL ALLYL ETHERS, POLYMERS AND POLYMERIC SOLID ELECTROLYTES
  申请人：MITSUI CHEMICALS, INC.

  公开号：EP0787749B1

  公开（公告）日：2003-04-02