银(I)D,L-天冬酰胺 | 458524-52-2

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 中文名称: 银(I)D,L-天冬酰胺
• 英文名称: silver(I) D,L-asparaginate
• CAS: 458524-52-2
• 化学式: Ag*C₄H₇N₂O₃
• 分子量: 238.979
• InChiKey: ZSHLCTXNJABCIC-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  -3.06
• 重原子数：
  10.0
• 可旋转键数：
  3.0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  109.24
• 氢给体数：
  2.0
• 氢受体数：
  4.0

反应信息

• 作为反应物：
  描述：

  银(I)D,L-天冬酰胺 以 水 为溶剂， 生成 银
  参考文献：
  名称：

  Abderhalden, E.; Kautzsch, K., Zeitschrift fur Physiologische Chemie, 1912, vol. 78, p. 115 - 127

  摘要：

  DOI：
• 作为产物：
  描述：

  DL-天冬酰胺一水物 、 silver(l) oxide 以 水 为溶剂， 生成 银(I)D,L-天冬酰胺
  参考文献：
  名称：

  Abderhalden, E.; Kautzsch, K., Zeitschrift fur Physiologische Chemie, 1912, vol. 78, p. 115 - 127

  摘要：

  DOI：

文献信息

• Gmelin Handbuch der Anorganischen Chemie, Gmelin Handbook: Ag: MVol.B6, 1.2.4.2, page 28 - 35
  作者：

  DOI：——

  日期：——
• Bruni, G.; Levi, G., Gazzetta Chimica Italiana, 1916, vol. 46 II, p. 235 - 246
  作者：Bruni, G.、Levi, G.

  DOI：——

  日期：——
• Gmelin Handbuch der Anorganischen Chemie, Gmelin Handbook: Ag: MVol.B6, 1.11.6, page 255 - 255
  作者：

  DOI：——

  日期：——
• Light-stable and antimicrobial active silver(I) complexes composed of triphenylphosphine and amino acid ligands: Synthesis, crystal structure, and antimicrobial activity of silver(I) complexes constructed with hard and soft donor atoms (∞{[Ag(L)(PPh3)]2} with L = α-ala− or asn− and n= 1 or 2)
  作者：Noriko Chikaraishi Kasuga、Misako Sato、Akifumi Amano、Akihiro Hara、Shinichiro Tsuruta、Akiyoshi Sugie、Kenji Nomiya

  DOI：10.1016/j.ica.2007.08.020

  日期：2008.4

  Three novel silver(I) complexes consisting of both hard Lewis bases (O and N atoms) and one soft Lewis base (P atom) ((DL-alpha-alaninato)(triphenylphosphine) silver(I) (1), (DL-asparaginato)(triphenylphosphine) silver(I) (2) and (L-asparaginato)(triphenylphosphine) silver(I) (3)) were prepared from stoichiometric reactions of amino acid-silver(I) complexes with PPh3 in a 1: 1 molar ratio in a mixed organic solvent. These silver(I) complexes were soluble in organic solvents but insoluble in water; they are also more light-stable as compared to the corresponding precursors, amino acid-silver(I) complexes. Their solid-state and solution structures were unequivocally characterized using elemental analysis, TG/DTA, FTIR, X-ray structure analysis, solution (H-1, C-13, and P-31) NMR and solid-state P-31 CPMAS NMR spectroscopy. The X-ray structure analysis of complexes 1 and 2 revealed that these complexes were dimers with an inversion center. Each silver(I) atom was coordinated in a distorted four-coordinate environment containing an AgNO2P core. Complexes 1 and 2 formed 1D and 2D networks in the crystal through intermolecular hydrogen bonding networks that can be described as (infinity)[Ag(DL-alpha-ala)(PPh3)](2) center dot 2H(2)O} and (2)(infinity)[Ag(DL-asn)(PPh3)](2) center dot 2H(2)O center dot 2EtOH}, respectively. Complexes 1-3 showed moderate to modest antimicrobial activities against selected bacteria and yeasts in a water-suspension system. (C) 2007 Elsevier B.V. All rights reserved.