4-(1-氧代丁氧基)丁酸 | 30470-15-6

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: 4-(1-氧代丁氧基)丁酸
• 英文名称: 4-Butyryloxy-butyric acid
• 英文别名: Butanoic acid, 4-(1-oxobutoxy)-；4-butanoyloxybutanoic acid
• CAS: 30470-15-6
• 化学式: C₈H₁₄O₄
• 分子量: 174.197
• InChiKey: ZPQSIEHAZYDJOH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.8
• 重原子数：
  12
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  63.6
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  butanoic acid 4-pentenyl ester 在 cobalt(II) acetate 氧气 作用下， 生成 4-(1-氧代丁氧基)丁酸
  参考文献：
  名称：

  Zamarlik,H., Comptes Rendus des Seances de l'Academie des Sciences, Serie C: Sciences Chimiques, 1970, vol. 271, p. 1138 - 1141

  摘要：

  DOI：

文献信息

• PIPERIDINE COMPOUNDS AS PCSK9 INHIBITORS
  申请人：SHENZHEN SALUBRIS PHARM CO LTD

  公开号：US20180305346A1

  公开（公告）日：2018-10-25

  One aspect of the invention relates to a series of new PCSK9 inhibitor compounds comprising piperidine ring structures, including compounds of formula (I) and/or pharmaceutically acceptable salts thereof. Another aspect of the invention relates to methods of treating PCSK9 receptor related diseases comprising administration of one or more compounds of formula (I) or a pharmaceutically acceptable salt thereof.

  这项发明的一个方面涉及一系列新的PCSK9抑制剂化合物，包括含有哌啶环结构的化合物，其中包括式(I)的化合物和/或其药用可接受的盐。该发明的另一个方面涉及治疗PCSK9受体相关疾病的方法，包括给予式(I)的一个或多个化合物或其药用可接受的盐。
• [EN] HERBICIDAL COMPOUNDS<br/>[FR] COMPOSÉS HERBICIDES
  申请人：SYNGENTA PARTICIPATIONS AG

  公开号：WO2018114584A1

  公开（公告）日：2018-06-28

  The present invention relates to compounds of Formula (I), (I) or an agronomically acceptable salt of said compounds wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10 and G are as defined herein. The invention further relates to herbicidal 10 compositions which comprise a compound of Formula (I), to their use for controlling weeds, in particular in crops of useful plants.

  本发明涉及式(I)、(II)化合物或其农学上可接受的盐，其中R1、R2、R3、R4、R5、R6、R7、R8、R9、R10和G的定义如本文所述。本发明还涉及包括式(I)化合物的除草剂组合物，以及它们在控制杂草方面的使用，特别是在有用植物的作物中。
• COMPOUNDS AND METHODS FOR THE TREATMENT OF PAIN
  申请人：Toth Istvan

  公开号：US20100130581A1

  公开（公告）日：2010-05-27

  This invention relates to derivatives of an endomorphin, or of an endomorphin analog, comprising at least one moiety selected from a lipid moiety, a cyclitol moiety and a saccharide moiety.

  本发明涉及内啡肽的衍生物或内啡肽类似物的衍生物，其中至少包括一种取自脂质基团、环糖基团和糖基团的基团。
• CONDUCTING AND SEMICONDUCTING ORGANIC MATERIALS
  申请人：Commonwealth Scientific and Industrial Research Organisation

  公开号：US20130289217A1

  公开（公告）日：2013-10-31

  A polymer comprising a conducting or semiconducting segment coupled to a polymer segment having an insulating polymer backbone, the polymer further comprising a RAFT functional group coupled to the polymer segment, wherein there is no RAFT functional group in between the conducting or semiconducting segment and the polymer segment.

  一种聚合物，包括一个导电或半导体段与一个具有绝缘聚合物骨架的聚合物段相耦合，该聚合物进一步包括与聚合物段相耦合的RAFT功能基团，其中在导电或半导体段与聚合物段之间没有RAFT功能基团。
• GRADIENT OPTICAL POLYMER NANOCOMPOSITES
  申请人：State of Oregon acting by and through the State Board of Higher Education on behalf of the Univers

  公开号：US20150023643A1

  公开（公告）日：2015-01-22

  Gradient index optical materials are formed by drop by drop dispensing of nanoparticle/monomer suspensions. Refractive index variations are defined by nanoparticle concentrations that can vary in three dimensions. Droplets of differing compositions can be mixed, and droplets or layers or droplets are partially cross-linked by exposure to ultraviolet radiation prior to dispensing additional droplets. Gradient index optical elements such as lenses, prisms, and waveguides can be formed in flexible polymer layers.

  渐变折射率光学材料是通过滴滴分配纳米颗粒/单体悬浮液形成的。折射率变化由纳米颗粒浓度在三个维度上变化定义。不同成分的液滴可以混合，液滴或液滴层可以在分配额外液滴之前通过紫外线辐射部分交联。可以在柔性聚合物层中形成渐变折射率光学元件，如透镜、棱镜和波导。