(2S)-2-(but-2-enoylamino)-3-phenylpropanoic acid | 38108-03-1

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: (2S)-2-(but-2-enoylamino)-3-phenylpropanoic acid
• CAS: 38108-03-1
• 化学式: C₁₃H₁₅NO₃
• 分子量: 233.267
• InChiKey: XHXLXGWBZWBLPZ-NSHDSACASA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  17
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.23
• 拓扑面积：
  66.4
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  氯乙基磺酰氯 、 (2S)-2-(but-2-enoylamino)-3-phenylpropanoic acid 以 氯仿 为溶剂， 生成
  参考文献：
  名称：

  N-acylated amino acids containing a??-chloroethylthio grouping

  摘要：

  DOI：

  10.1007/bf00851222
• 作为产物：
  描述：

  L-苯丙氨酸 、 巴豆酰氯 在 sodium hydroxide 作用下， 生成 (2S)-2-(but-2-enoylamino)-3-phenylpropanoic acid
  参考文献：
  名称：

  N-acylated amino acids containing a??-chloroethylthio grouping

  摘要：

  DOI：

  10.1007/bf00851222

文献信息

• Composition containing a penem or carbapenem antibiotic
  申请人：SANKYO COMPANY LIMITED

  公开号：EP0178911A2

  公开（公告）日：1986-04-23

  57 Administration of an N-acylated amino acid (ornithine, lysine, phenylglycine or phenylalanine) in association with a penem or carbapenem antibiotic relieves or eliminates the renal problems associated with administration of the antibiotic alone. The amino acid and antibiotic may be formulated together as a composition or administered separately, either simultaneously or sequentially. A pharmaceutical composition may be prepared simply by mixing the two components.

  57 将 N-酰化氨基酸（鸟氨酸、赖氨酸、苯甘氨酸或苯丙氨酸）与培南类或碳青霉烯类抗生素联合给药，可缓解或消除与单独给药抗生素相关的肾脏问题。 氨基酸和抗生素可一起配制成组合物，也可同时或依次单独给药。 只需将两种成分混合即可制备成药物组合物。
• CURABLE DENTAL COMPOSITION
  申请人：Tokuyama Dental Corporation

  公开号：EP3682862A1

  公开（公告）日：2020-07-22

  A dental curable composition which comprises a radically polymerizable monomer component (A), a polymerizing catalyst (B) and an inorganic granular material (C), characterized in that: the radically polymerizable monomer component (A) contains a bifunctional monomer (A-1) represented by the following formula (α),         RP-SP1-RP     (α) where, Rp is a radically polymerizable group represented by CH2=C(R)-COO- or CH2=C(R)-CONH-, wherein R is a hydrogen atom or a hydrocarbon group having 1 to 3 carbon atoms, and SP1 is a hydrocarbon group having 5 to 15 carbon atoms, and the content of the bifunctional monomer (A-1) in the radically polymerizable monomer component (A) is 5 to 40% by mass under a condition that the content of a diluting monomer (A-2) represented by the following formula (β),         RP-SP2-RP     (β) where, Rp is as defined in the above formula (α), and SP2 is an aliphatic hydrocarbon group different from SP1, an oxygen-containing aliphatic hydrocarbon group having not less than 2 oxygen atoms, or an oxygen-containing aromatic hydrocarbon group having not less than 3 oxygen atoms, is zero or not more than 10% by mass.

  一种牙科固化组合物，由可径向聚合的单体组分（A）、聚合催化剂（B）和无机颗粒材料（C）组成，其特征在于：可径向聚合的单体组分（A）含有由下式（α）表示的双官能团单体（A-1）、 RP-SP1-RP (α) 其中，Rp 是由 CH2=C(R)-COO- 或 =C(R)-CONH- 表示的可辐射聚合基团，其中 R 是氢原子或具有 1 至 3 个碳原子的烃基，SP1 是具有 5 至 15 个碳原子的烃基，双官能团单体（A-1）在可辐射聚合单体组分（A）中的含量按质量计为 5 至 40%，条件是由下式（β）表示的稀释单体（A-2）的含量、 RP-SP2-RP (β) 其中，Rp 如上式（α）所定义，SP2 是不同于 SP1 的脂肪族烃基、具有不少于 2 个氧原子的含 氧脂肪族烃基或具有不少于 3 个氧原子的含氧芳香族烃基、 质量百分比为零或不超过 10%。
• Dental Curable Composition
  申请人：Tokuyama Dental Corporation

  公开号：US20200253835A1

  公开（公告）日：2020-08-13

  A dental curable composition which comprises a radically polymerizable monomer component (A), a polymerizing catalyst (B) and an inorganic granular material (C), characterized in that: the radically polymerizable monomer component (A) contains a bifunctional monomer (A-1) represented by the following formula (α), R P —SP 1 —R P (α) where, R P is a radically polymerizable group represented by CH 2 ═C(R)—COO— or CH 2 ═C(R)—CONH—, wherein R is a hydrogen atom or a hydrocarbon group having 1 to 3 carbon atoms, and SP 1 is a hydrocarbon group having 5 to 15 carbon atoms, and the content of the bifunctional monomer (A-1) in the radically polymerizable monomer component (A) is 5 to 40% by mass under a condition that the content of a diluting monomer (A-2) represented by the following formula (β), R P —SP 2 —R P (β) where, R P is as defined in the above formula (α), and SP 2 is an aliphatic hydrocarbon group different from. SP 1 , an oxygen-containing aliphatic hydrocarbon group having not less than 2 oxygen atoms, or an oxygen-containing aromatic hydrocarbon group having not less than 3 oxygen atoms, is zero or not more than 10% by mass.
• US4757066A
  申请人：——

  公开号：US4757066A

  公开（公告）日：1988-07-12