(Z)-1-(1-phenyl-2-(p-chlorophenylselanyl)vinyl)-1H-imidazole | 1544201-52-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (Z)-1-(1-phenyl-2-(p-chlorophenylselanyl)vinyl)-1H-imidazole
• 英文别名: 1-[(Z)-2-(4-chlorophenyl)selanyl-1-phenylethenyl]imidazole
• CAS: 1544201-52-6
• 化学式: C₁₇H₁₃ClN₂Se
• 分子量: 359.717
• InChiKey: GOTZORDWXAMPLL-ATVHPVEESA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.41
• 重原子数：
  21
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  17.8
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  咪唑 、 1-(4-chlorophenyl)seleno-2-phenylacetylene 以 N,N-二甲基甲酰胺 为溶剂， 反应 96.0h， 以40%的产率得到(Z)-1-(1-phenyl-2-(p-chlorophenylselanyl)vinyl)-1H-imidazole
  参考文献：
  名称：

  Synthesis of (Z)-N-alkenyl-β-arylselanyl imidazoles via additive-free nucleophilic addition of imidazole to arylselanylalkynes

  摘要：

  We present herein our results on the nucleophilic addition of imidazole to a range of arylselanylalkynes by simple heating in DMF without any additives to give (Z)-1-(1-organyl-(2-arylselanyl)vinyl)-1H-imidazoles. The reactions were performed under mild conditions with a range of arylselanylalkynes in good yields and with high regio- and stereoselectivity to give the respective (Z)-arylselanyl alkene as the only isomer. (C) 2013 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2013.12.058

文献信息

• Synthesis of (Z)-N-alkenyl-β-arylselanyl imidazoles via additive-free nucleophilic addition of imidazole to arylselanylalkynes
  作者：Liane K. Soares、Renata G. Lara、Raquel G. Jacob、Eder J. Lenardão、Diego Alves、Gelson Perin

  DOI：10.1016/j.tetlet.2013.12.058

  日期：2014.1

  We present herein our results on the nucleophilic addition of imidazole to a range of arylselanylalkynes by simple heating in DMF without any additives to give (Z)-1-(1-organyl-(2-arylselanyl)vinyl)-1H-imidazoles. The reactions were performed under mild conditions with a range of arylselanylalkynes in good yields and with high regio- and stereoselectivity to give the respective (Z)-arylselanyl alkene as the only isomer. (C) 2013 Elsevier Ltd. All rights reserved.