3-Methyl-isoxazole-5-carboxylic acid butylamide | 27144-52-1

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 3-Methyl-isoxazole-5-carboxylic acid butylamide
• 英文别名: N-butyl-3-methyl-1,2-oxazole-5-carboxamide
• CAS: 27144-52-1
• 化学式: C₉H₁₄N₂O₂
• mdl: MFCD14778145
• 分子量: 182.222
• InChiKey: CCURVDGCENCCEI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.6
• 重原子数：
  13
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.555
• 拓扑面积：
  55.1
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• SUBSTITUTED AZASPIRO(4.5)DECANE DERIVATIVES
  申请人：Grünenthal GmbH

  公开号：EP3169666B1

  公开（公告）日：2018-06-06
• Substituted Azaspiro(4.5)Decane Derivatives
  申请人：Gruenenthal GmbH

  公开号：US20170210734A1

  公开（公告）日：2017-07-27

  The invention relates to substituted spirocyclic cyclohexane derivatives which have an affinity for the μ opioid receptor and/or the ORL1 receptor, processes for the preparation thereof, medicaments containing these compounds and the use of these compounds for the preparation of medicaments.
• [EN] SUBSTITUTED AZASPIRO(4.5)DECANE DERIVATIVES<br/>[FR] DÉRIVÉS D'AZASPIRO(4,5)DÉCANE SUBSTITUÉS
  申请人：GRUENENTHAL GMBH

  公开号：WO2016008582A1

  公开（公告）日：2016-01-21

  The invention relates to substituted spirocyclic cyclohexane derivatives which have an affinity for the μ opioid receptor and/or the ORL1 receptor, processes for the preparation thereof, medicaments containing these compounds and the use of these compounds for the preparation of medicaments.