2-Indanyl-aethyl-keton | 33982-87-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 茚满类
• 英文名称: 2-Indanyl-aethyl-keton
• 英文别名: 1-indan-2-yl-propan-1-one；2¹-Oxo-2-propyl-hydrinden；α-Oxo-α-(hydrindyl-(2))-propan；2-Propionyl-hydrinden；Aethyl-β-hydrindyl-keton；1-Indan-2-yl-propan-1-on；1-(2,3-dihydro-1H-inden-2-yl)propan-1-one
• CAS: 33982-87-5
• 化学式: C₁₂H₁₄O
• 分子量: 174.243
• InChiKey: AAMGJKUNSVUHEK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  13
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.42
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  diethylzinc 、 alkaline earth salt of/the/ methylsulfuric acid 生成 2-Indanyl-aethyl-keton
  参考文献：
  名称：

  Perkin; Revay, Chemische Berichte, 1893, vol. 26, p. 2253

  摘要：

  DOI：

文献信息

• Methods and Compositions for Selectin Inhibition
  申请人：Kaila Neelu

  公开号：US20080242700A1

  公开（公告）日：2008-10-02

  The present teachings relate to compounds of formula I: wherein the constituent variables are defined herein. Compounds of the present teachings can act as antagonists of the mammalian adhesion proteins known as selecting. Methods for treating selectin mediated disorders are provided, which include administration of these compounds in a therapeutically effective amount.

  本教学涉及到式I的化合物： 其中组成变量在此定义。本教学的化合物可以作为被称为选择素的哺乳动物粘附蛋白的拮抗剂。提供了治疗选择素介导的疾病的方法，其中包括以治疗有效剂量给予这些化合物。
• TRICYCLIC PYRIDO-CARBOXAMIDE DERIVATIVES AS ROCK INHIBITORS
  申请人：BRISTOL-MYERS SQUIBB COMPANY

  公开号：US20160152627A1

  公开（公告）日：2016-06-02

  The present invention provides compounds of Formula (I): or stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, wherein all the variables are as defined herein. These compounds are selective ROCK inhibitors. This invention also relates to pharmaceutical compositions comprising these compounds and methods of treating cardiovascular, smooth muscle, oncologic, neuropathologic, autoimmune, fibrotic, and/or inflammatory disorders using the same.
• US9663529B2
  申请人：——

  公开号：US9663529B2

  公开（公告）日：2017-05-30