9-(10-Hydroxy-12-oxapentacyclo[11.8.0.02,11.03,8.015,20]henicosa-1(21),2(11),3,5,7,9,13,15,17,19-decaen-9-yl)-14-nonyl-12-oxapentacyclo[11.8.0.02,11.03,8.015,20]henicosa-1(21),2(11),3,5,7,9,13,15,17,19-decaen-10-ol | 1578258-79-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 萘并呋喃类
• 英文名称: 9-(10-Hydroxy-12-oxapentacyclo[11.8.0.02,11.03,8.015,20]henicosa-1(21),2(11),3,5,7,9,13,15,17,19-decaen-9-yl)-14-nonyl-12-oxapentacyclo[11.8.0.02,11.03,8.015,20]henicosa-1(21),2(11),3,5,7,9,13,15,17,19-decaen-10-ol
• 英文别名: 9-(10-hydroxy-12-oxapentacyclo[11.8.0.02,11.03,8.015,20]henicosa-1(21),2(11),3,5,7,9,13,15,17,19-decaen-9-yl)-14-nonyl-12-oxapentacyclo[11.8.0.02,11.03,8.015,20]henicosa-1(21),2(11),3,5,7,9,13,15,17,19-decaen-10-ol
• CAS: 1578258-79-3
• 化学式: C₄₉H₄₀O₄
• 分子量: 692.854
• InChiKey: TZGWJUOLMCOODO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  15.6
• 重原子数：
  53
• 可旋转键数：
  9
• 环数：
  10.0
• sp3杂化的碳原子比例：
  0.18
• 拓扑面积：
  66.7
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  9-(10-Hydroxy-12-oxapentacyclo[11.8.0.02,11.03,8.015,20]henicosa-1(21),2(11),3,5,7,9,13,15,17,19-decaen-9-yl)-14-nonyl-12-oxapentacyclo[11.8.0.02,11.03,8.015,20]henicosa-1(21),2(11),3,5,7,9,13,15,17,19-decaen-10-ol 在 甲烷磺酸 作用下， 以 邻二甲苯 为溶剂， 反应 108.0h， 以32%的产率得到18-Nonyl-20,23,26-trioxaundecacyclo[22.19.0.02,22.03,8.09,21.010,19.012,17.025,37.027,36.029,34.038,43]tritetraconta-1(24),2(22),3,5,7,9(21),10,12,14,16,18,25(37),27,29,31,33,35,38,40,42-icosaene
  参考文献：
  名称：

  Synthesis and Properties of Butterfly-Shaped Expanded Naphthofuran Derivatives

  摘要：

  The construction of dinaphtho[2,1-b;2',3'-d]furan-6-ol was developed via a dehydration reaction involving two molecules of 2,3-dihydroxynaphthalene in the presence of a strong acid. Starting from the dinaphthofuran, a variety of butterfly shaped derivatives were synthesized. The optical properties of these compounds were investigated with special attention to the dihedral angle formed by adjacent dinaphthofuran rings and/or the sizes of the fused aromatic rings.

  DOI：

  10.1021/jo500085a
• 作为产物：
  描述：

  10-Butoxy-9-(10-butoxy-12-oxapentacyclo[11.8.0.02,11.03,8.015,20]henicosa-1(21),2(11),3,5,7,9,13,15,17,19-decaen-9-yl)-14-nonyl-12-oxapentacyclo[11.8.0.02,11.03,8.015,20]henicosa-1(21),2(11),3,5,7,9,13,15,17,19-decaene 在 三溴化硼 作用下， 以 二氯甲烷 为溶剂， 反应 1.0h， 以87%的产率得到9-(10-Hydroxy-12-oxapentacyclo[11.8.0.02,11.03,8.015,20]henicosa-1(21),2(11),3,5,7,9,13,15,17,19-decaen-9-yl)-14-nonyl-12-oxapentacyclo[11.8.0.02,11.03,8.015,20]henicosa-1(21),2(11),3,5,7,9,13,15,17,19-decaen-10-ol
  参考文献：
  名称：

  Synthesis and Properties of Butterfly-Shaped Expanded Naphthofuran Derivatives

  摘要：

  The construction of dinaphtho[2,1-b;2',3'-d]furan-6-ol was developed via a dehydration reaction involving two molecules of 2,3-dihydroxynaphthalene in the presence of a strong acid. Starting from the dinaphthofuran, a variety of butterfly shaped derivatives were synthesized. The optical properties of these compounds were investigated with special attention to the dihedral angle formed by adjacent dinaphthofuran rings and/or the sizes of the fused aromatic rings.

  DOI：

  10.1021/jo500085a

文献信息

• Synthesis and Properties of Butterfly-Shaped Expanded Naphthofuran Derivatives
  作者：Kentaro Nakanishi、Takahiro Sasamori、Kouji Kuramochi、Norihiro Tokitoh、Takeo Kawabata、Kazunori Tsubaki

  DOI：10.1021/jo500085a

  日期：2014.3.21

  The construction of dinaphtho[2,1-b;2',3'-d]furan-6-ol was developed via a dehydration reaction involving two molecules of 2,3-dihydroxynaphthalene in the presence of a strong acid. Starting from the dinaphthofuran, a variety of butterfly shaped derivatives were synthesized. The optical properties of these compounds were investigated with special attention to the dihedral angle formed by adjacent dinaphthofuran rings and/or the sizes of the fused aromatic rings.