N,N-bis[(5-azido-2-bromophenyl)methyl]-1-(3-azidophenyl)ethanamine | 941703-23-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N,N-bis[(5-azido-2-bromophenyl)methyl]-1-(3-azidophenyl)ethanamine
• CAS: 941703-23-7
• 化学式: C₂₂H₁₈Br₂N₁₀
• 分子量: 582.26
• InChiKey: RUQVKXBYEKGFNW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  9.3
• 重原子数：
  34
• 可旋转键数：
  9
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.18
• 拓扑面积：
  46.3
• 氢给体数：
  0
• 氢受体数：
  7

反应信息

• 作为反应物：
  描述：

  N,N-bis[(5-azido-2-bromophenyl)methyl]-1-(3-azidophenyl)ethanamine 、 1,1,1-tris(diphenylphosphanylmethyl)-2-methylpropane 以 乙醚 、 氘代氯仿 为溶剂， 反应 27.0h， 以55%的产率得到
  参考文献：
  名称：

  Center-to-propeller and propeller-to-propeller stereocontrol in a series of macrobicyclic tri-λ5-phosphazenes

  摘要：

  Center-to-propeller stereocontrol in a family of macrobicyclic, double-propeller shaped tri-lambda(5)-triphosphazenes remains constant in the upper tribenzylamine fragment as the size of the pivotal group at the lower tris(phosphane) fragment is gradually increased. In contrast the propeller-to-propeller stereocontrol diminishes as a result of the increasing conformational lability in the lower hemisphere. (C) 2007 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2007.03.087
• 作为产物：
  描述：

  3-(1-羟乙基)苯胺 在 盐酸 、 焦磷酸硫胺素 、 sodium carbonate 、 sodium nitrite 、 偶氮二甲酸二乙酯 作用下， 以 四氢呋喃 、 乙腈 为溶剂， 反应 61.5h， 生成 N,N-bis[(5-azido-2-bromophenyl)methyl]-1-(3-azidophenyl)ethanamine
  参考文献：
  名称：

  Center-to-propeller and propeller-to-propeller stereocontrol in a series of macrobicyclic tri-λ5-phosphazenes

  摘要：

  Center-to-propeller stereocontrol in a family of macrobicyclic, double-propeller shaped tri-lambda(5)-triphosphazenes remains constant in the upper tribenzylamine fragment as the size of the pivotal group at the lower tris(phosphane) fragment is gradually increased. In contrast the propeller-to-propeller stereocontrol diminishes as a result of the increasing conformational lability in the lower hemisphere. (C) 2007 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2007.03.087

文献信息

• Center-to-propeller and propeller-to-propeller stereocontrol in a series of macrobicyclic tri-λ5-phosphazenes
  作者：Mateo Alajarín、Carmen López-Leonardo、José Berná、Pilar Sánchez-Andrada

  DOI：10.1016/j.tetlet.2007.03.087

  日期：2007.5

  Center-to-propeller stereocontrol in a family of macrobicyclic, double-propeller shaped tri-lambda(5)-triphosphazenes remains constant in the upper tribenzylamine fragment as the size of the pivotal group at the lower tris(phosphane) fragment is gradually increased. In contrast the propeller-to-propeller stereocontrol diminishes as a result of the increasing conformational lability in the lower hemisphere. (C) 2007 Elsevier Ltd. All rights reserved.